PDGFRB

ENSG00000113721 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004992 platelet activating factor receptor activity
GO:0005017 platelet-derived growth factor-activated receptor activity
GO:0005019 platelet-derived growth factor beta-receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0038085 vascular endothelial growth factor binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048407 platelet-derived growth factor binding

Drugs

Drug name Description
BECAPLERMIN Platelet-derived growth factor receptor agonist
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor

Diseases

Disease Name
MPN
AML
CMML
CML

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000100393 EP300 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.991088 View
ENSG00000005339 CREBBP ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.989057 View
ENSG00000012048 BRCA1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.986684 View
ENSG00000113721 PDGFRB ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.98449 View
ENSG00000113721 PDGFRB ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.984216 View
ENSG00000110048 OSBP ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.984139 View
ENSG00000102683 SGCG ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.983834 View
ENSG00000113721 PDGFRB ENSG00000126583 PRKCG H. sapiens SDL Slorth 0.9831 View
ENSG00000072736 NFATC3 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982753 View
ENSG00000106346 USP42 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982686 View
ENSG00000099785 MARCH2 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982664 View
ENSG00000113721 PDGFRB ENSG00000149930 TAOK2 H. sapiens SDL Slorth 0.982361 View
ENSG00000100239 PPP6R2 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982346 View
ENSG00000067829 IDH3G ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982344 View
ENSG00000077380 DYNC1I2 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982181 View
ENSG00000077935 SMC1B ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982181 View
ENSG00000079156 OSBPL6 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982181 View
ENSG00000100372 SLC25A17 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982168 View
ENSG00000086619 ERO1B ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.982106 View
ENSG00000105290 APLP1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.981874 View
ENSG00000113721 PDGFRB ENSG00000178573 MAF H. sapiens SDL Slorth 0.981864 View
ENSG00000088367 EPB41L1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.981519 View
ENSG00000007908 SELE ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.98139 View
ENSG00000021574 SPAST ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.981361 View
ENSG00000112679 DUSP22 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.981306 View
ENSG00000100982 PCIF1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.980775 View
ENSG00000100320 RBFOX2 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.980698 View
ENSG00000109670 FBXW7 ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.980582 View
ENSG00000113721 PDGFRB ENSG00000147010 SH3KBP1 H. sapiens SDL Slorth 0.980458 View
ENSG00000113721 PDGFRB ENSG00000120149 MSX2 H. sapiens SDL Slorth 0.980288 View
ENSG00000113721 PDGFRB ENSG00000169714 CNBP H. sapiens SDL Slorth 0.980264 View
ENSG00000066923 STAG3 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.980122 View
ENSG00000070718 AP3M2 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.980122 View
ENSG00000101365 IDH3B ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.979873 View
ENSG00000049323 LTBP1 ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.979778 View
ENSG00000004848 ARX ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.979602 View
ENSG00000113721 PDGFRB ENSG00000138756 BMP2K H. sapiens SDL Slorth 0.97958 View
ENSG00000113721 PDGFRB ENSG00000159461 AMFR H. sapiens SDL Slorth 0.979235 View
ENSG00000079335 CDC14A ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.979074 View
ENSG00000113721 PDGFRB ENSG00000198087 CD2AP H. sapiens SDL Slorth 0.978805 View