SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000136807 CDK9 ENSG00000141646 SMAD4 H. sapiens SSL BioGRID 1.0 View
ENSG00000198793 MTOR ENSG00000141646 SMAD4 H. sapiens SSL BioGRID 1.0 View
ENSG00000141646 SMAD4 ENSG00000166483 WEE1 H. sapiens SSL BioGRID 1.0 View
ENSG00000141646 SMAD4 ENSG00000157514 TSC22D3 H. sapiens SDL Slorth 0.98737 View
ENSG00000141646 SMAD4 ENSG00000154310 TNIK H. sapiens SDL Slorth 0.986224 View
ENSG00000141646 SMAD4 ENSG00000180008 SOCS4 H. sapiens SDL Slorth 0.986101 View
ENSG00000141646 SMAD4 ENSG00000221823 PPP3R1 H. sapiens SDL Slorth 0.985913 View
ENSG00000141646 SMAD4 ENSG00000165699 TSC1 H. sapiens SDL Slorth 0.985478 View
ENSG00000130703 OSBPL2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985349 View
ENSG00000102996 MMP15 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985346 View
ENSG00000141646 SMAD4 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.985317 View
ENSG00000079156 OSBPL6 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985146 View
ENSG00000135604 STX11 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985104 View
ENSG00000099785 MARCH2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985104 View
ENSG00000086619 ERO1B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985104 View
ENSG00000100372 SLC25A17 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985096 View
ENSG00000066455 GOLGA5 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985079 View
ENSG00000100239 PPP6R2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985078 View
ENSG00000116990 MYCL ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985036 View
ENSG00000110048 OSBP ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.985035 View
ENSG00000102683 SGCG ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984897 View
ENSG00000113240 CLK4 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984889 View
ENSG00000129354 AP1M2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984872 View
ENSG00000138829 FBN2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984868 View
ENSG00000134871 COL4A2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984868 View
ENSG00000127329 PTPRB ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984868 View
ENSG00000136014 USP44 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98472 View
ENSG00000007908 SELE ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984718 View
ENSG00000126785 RHOJ ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984714 View
ENSG00000120500 ARR3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98468 View
ENSG00000139668 WDFY2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98468 View
ENSG00000088367 EPB41L1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98465 View
ENSG00000104892 KLC3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984283 View
ENSG00000141646 SMAD4 ENSG00000160007 ARHGAP35 H. sapiens SDL Slorth 0.984215 View
ENSG00000077935 SMC1B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98411 View
ENSG00000077380 DYNC1I2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984102 View
ENSG00000021574 SPAST ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.984102 View
ENSG00000141646 SMAD4 ENSG00000171435 KSR2 H. sapiens SDL Slorth 0.984083 View
ENSG00000141646 SMAD4 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.984038 View
ENSG00000125656 CLPP ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983918 View