SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077092 RARB ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979953 View
ENSG00000141646 SMAD4 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.979949 View
ENSG00000120539 MASTL ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979941 View
ENSG00000141646 SMAD4 ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.979801 View
ENSG00000141646 SMAD4 ENSG00000185022 MAFF H. sapiens SDL Slorth 0.979794 View
ENSG00000100228 RAB36 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979782 View
ENSG00000138594 TMOD3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979782 View
ENSG00000140199 SLC12A6 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979782 View
ENSG00000085185 BCORL1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979782 View
ENSG00000141646 SMAD4 ENSG00000169813 HNRNPF H. sapiens SSL Slorth 0.979778 View
ENSG00000079337 RAPGEF3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979673 View
ENSG00000106346 USP42 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979646 View
ENSG00000132386 SERPINF1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979642 View
ENSG00000095397 WHRN ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979623 View
ENSG00000141646 SMAD4 ENSG00000156475 PPP2R2B H. sapiens SDL Slorth 0.979595 View
ENSG00000131941 RHPN2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979589 View
ENSG00000015285 WAS ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979507 View
ENSG00000111218 PRMT8 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979432 View
ENSG00000125967 NECAB3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979419 View
ENSG00000005882 PDK2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979419 View
ENSG00000105204 DYRK1B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979368 View
ENSG00000115616 SLC9A2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979341 View
ENSG00000141646 SMAD4 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.979289 View
ENSG00000004848 ARX ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979238 View
ENSG00000141646 SMAD4 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.979192 View
ENSG00000141646 SMAD4 ENSG00000198399 ITSN2 H. sapiens SDL Slorth 0.979095 View
ENSG00000141646 SMAD4 ENSG00000143569 UBAP2L H. sapiens SDL Slorth 0.979095 View
ENSG00000100393 EP300 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979081 View
ENSG00000141646 SMAD4 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.979024 View
ENSG00000006468 ETV1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.978957 View
ENSG00000141646 SMAD4 ENSG00000147614 ATP6V0D2 H. sapiens SDL Slorth 0.978883 View
ENSG00000141646 SMAD4 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.978865 View
ENSG00000141646 SMAD4 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.978852 View
ENSG00000090889 KIF4A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.978827 View
ENSG00000104140 RHOV ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.978818 View
ENSG00000112246 SIM1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.978818 View
ENSG00000141646 SMAD4 ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.978736 View
ENSG00000125740 FOSB ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.978726 View
ENSG00000087995 METTL2A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.978665 View
ENSG00000133703 KRAS ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.978663 View