SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000114554 PLXNA1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977007 View
ENSG00000141646 SMAD4 ENSG00000170734 POLH H. sapiens SSL Slorth 0.977005 View
ENSG00000141646 SMAD4 ENSG00000143033 MTF2 H. sapiens SDL Slorth 0.976988 View
ENSG00000141646 SMAD4 ENSG00000171960 PPIH H. sapiens SSL Slorth 0.97698 View
ENSG00000137673 MMP7 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.976918 View
ENSG00000141646 SMAD4 ENSG00000170345 FOS H. sapiens SSL Slorth 0.976879 View
ENSG00000141646 SMAD4 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.976844 View
ENSG00000130766 SESN2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.976738 View
ENSG00000141646 SMAD4 ENSG00000168646 AXIN2 H. sapiens SDL Slorth 0.976714 View
ENSG00000141646 SMAD4 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.976704 View
ENSG00000141646 SMAD4 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.976682 View
ENSG00000141646 SMAD4 ENSG00000160224 AIRE H. sapiens SDL Slorth 0.976666 View
ENSG00000141646 SMAD4 ENSG00000157601 MX1 H. sapiens SDL Slorth 0.976654 View
ENSG00000111049 MYF5 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.976599 View
ENSG00000136750 GAD2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.976587 View
ENSG00000141646 SMAD4 ENSG00000168283 BMI1 H. sapiens SSL Slorth 0.976534 View
ENSG00000067225 PKM ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.97647 View
ENSG00000141646 SMAD4 ENSG00000143420 ENSA H. sapiens SDL Slorth 0.976462 View
ENSG00000141646 SMAD4 ENSG00000152284 TCF7L1 H. sapiens SDL Slorth 0.976438 View
ENSG00000112319 EYA4 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.976273 View
ENSG00000141646 SMAD4 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.976235 View
ENSG00000080224 EPHA6 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.976138 View
ENSG00000134363 FST ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.976122 View
ENSG00000141646 SMAD4 ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.976094 View
ENSG00000141646 SMAD4 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.976071 View
ENSG00000141646 SMAD4 ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.976037 View
ENSG00000141646 SMAD4 ENSG00000171223 JUNB H. sapiens SSL Slorth 0.976029 View
ENSG00000141646 SMAD4 ENSG00000144852 NR1I2 H. sapiens SDL Slorth 0.976004 View
ENSG00000141646 SMAD4 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.975965 View
ENSG00000141646 SMAD4 ENSG00000183955 KMT5A H. sapiens SDL Slorth 0.975892 View
ENSG00000096717 SIRT1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.975837 View
ENSG00000141646 SMAD4 ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.975795 View
ENSG00000141646 SMAD4 ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.975793 View
ENSG00000132466 ANKRD17 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.975773 View
ENSG00000141646 SMAD4 ENSG00000174775 HRAS H. sapiens SDL Slorth 0.975769 View
ENSG00000104129 DNAJC17 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.975761 View
ENSG00000141646 SMAD4 ENSG00000148516 ZEB1 H. sapiens SDL Slorth 0.975751 View
ENSG00000141646 SMAD4 ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.975749 View
ENSG00000117625 RCOR3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.975745 View
ENSG00000124782 RREB1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.975732 View