DNMT3A - HDAC3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DNMT3A	ENSG00000119772	AML	AZACITIDINE DECITABINE	DNA binding chromatin binding DNA (cytosine-5-)-methyltransferase activity protein binding DNA-methyltransferase activity identical protein binding unmethylated CpG binding metal ion binding DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	No GO terms in record
HDAC3	ENSG00000171720	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	chromatin binding transcription corepressor activity histone deacetylase activity protein binding transcription factor binding enzyme binding cyclin binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity histone deacetylase binding NF-kappaB binding	RPD3 (S. cerevisiae) Hdac3 (D. melanogaster)