DNMT3A - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DNMT3A	ENSG00000119772	AML	AZACITIDINE DECITABINE	DNA binding chromatin binding DNA (cytosine-5-)-methyltransferase activity protein binding DNA-methyltransferase activity identical protein binding unmethylated CpG binding metal ion binding DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	No GO terms in record
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)