RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000047932 GOPC ENSG00000165731 RET H. sapiens SSL Slorth 0.880846 View
ENSG00000162434 JAK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.880824 View
ENSG00000130396 AFDN ENSG00000165731 RET H. sapiens SSL Slorth 0.880561 View
ENSG00000120438 TCP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.880468 View
ENSG00000106993 CDC37L1 ENSG00000165731 RET H. sapiens SSL Slorth 0.88041 View
ENSG00000164362 TERT ENSG00000165731 RET H. sapiens SSL Slorth 0.880327 View
ENSG00000119718 EIF2B2 ENSG00000165731 RET H. sapiens SSL Slorth 0.880215 View
ENSG00000069329 VPS35 ENSG00000165731 RET H. sapiens SSL Slorth 0.880174 View
ENSG00000127337 YEATS4 ENSG00000165731 RET H. sapiens SSL Slorth 0.879289 View
ENSG00000165731 RET ENSG00000185591 SP1 H. sapiens SSL Slorth 0.878985 View
ENSG00000160075 SSU72 ENSG00000165731 RET H. sapiens SSL Slorth 0.878447 View
ENSG00000102981 PARD6A ENSG00000165731 RET H. sapiens SSL Slorth 0.878203 View
ENSG00000071242 RPS6KA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.878203 View
ENSG00000123159 GIPC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.877996 View
ENSG00000165731 RET ENSG00000169032 MAP2K1 H. sapiens SSL Slorth 0.877841 View
ENSG00000137076 TLN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.877673 View
ENSG00000076984 MAP2K7 ENSG00000165731 RET H. sapiens SSL Slorth 0.877274 View
ENSG00000109339 MAPK10 ENSG00000165731 RET H. sapiens SSL Slorth 0.877174 View
ENSG00000165731 RET ENSG00000170315 UBB H. sapiens SSL Slorth 0.87712 View
ENSG00000153147 SMARCA5 ENSG00000165731 RET H. sapiens SSL Slorth 0.877103 View
ENSG00000144566 RAB5A ENSG00000165731 RET H. sapiens SSL Slorth 0.877033 View
ENSG00000148737 TCF7L2 ENSG00000165731 RET H. sapiens SSL Slorth 0.877003 View
ENSG00000150457 LATS2 ENSG00000165731 RET H. sapiens SSL Slorth 0.876859 View
ENSG00000048052 HDAC9 ENSG00000165731 RET H. sapiens SSL Slorth 0.876785 View
ENSG00000112685 EXOC2 ENSG00000165731 RET H. sapiens SSL Slorth 0.876784 View
ENSG00000164032 H2AFZ ENSG00000165731 RET H. sapiens SSL Slorth 0.8766 View
ENSG00000160691 SHC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.876559 View
ENSG00000127955 GNAI1 ENSG00000165731 RET H. sapiens SSL Slorth 0.876185 View
ENSG00000158402 CDC25C ENSG00000165731 RET H. sapiens SSL Slorth 0.876076 View
ENSG00000122512 PMS2 ENSG00000165731 RET H. sapiens SSL Slorth 0.876019 View
ENSG00000054116 TRAPPC3 ENSG00000165731 RET H. sapiens SSL Slorth 0.875956 View
ENSG00000119707 RBM25 ENSG00000165731 RET H. sapiens SSL Slorth 0.875846 View
ENSG00000165731 RET ENSG00000166483 WEE1 H. sapiens SSL Slorth 0.875828 View
ENSG00000079277 MKNK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.875605 View
ENSG00000145604 SKP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.875566 View
ENSG00000165731 RET ENSG00000172936 MYD88 H. sapiens SSL Slorth 0.875483 View
ENSG00000103653 CSK ENSG00000165731 RET H. sapiens SSL Slorth 0.875275 View
ENSG00000089154 GCN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.875029 View
ENSG00000141968 VAV1 ENSG00000165731 RET H. sapiens SSL Slorth 0.875025 View
ENSG00000126561 STAT5A ENSG00000165731 RET H. sapiens SSL Slorth 0.875007 View