RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000075711 DLG1 ENSG00000165731 RET H. sapiens SSL Slorth 0.90103 View
ENSG00000079387 SENP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.900738 View
ENSG00000165731 RET ENSG00000169750 RAC3 H. sapiens SDL Slorth 0.900679 View
ENSG00000072401 UBE2D1 ENSG00000165731 RET H. sapiens SSL Slorth 0.900664 View
ENSG00000136986 DERL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.900562 View
ENSG00000077721 UBE2A ENSG00000165731 RET H. sapiens SSL Slorth 0.900453 View
ENSG00000082898 XPO1 ENSG00000165731 RET H. sapiens SDL Slorth 0.900385 View
ENSG00000041357 PSMA4 ENSG00000165731 RET H. sapiens SDL Slorth 0.900218 View
ENSG00000115942 ORC2 ENSG00000165731 RET H. sapiens SSL Slorth 0.900093 View
ENSG00000103479 RBL2 ENSG00000165731 RET H. sapiens SSL Slorth 0.899896 View
ENSG00000152818 UTRN ENSG00000165731 RET H. sapiens SSL Slorth 0.899891 View
ENSG00000130382 MLLT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.899336 View
ENSG00000115464 USP34 ENSG00000165731 RET H. sapiens SSL Slorth 0.898432 View
ENSG00000130811 EIF3G ENSG00000165731 RET H. sapiens SSL Slorth 0.898351 View
ENSG00000058729 RIOK2 ENSG00000165731 RET H. sapiens SSL Slorth 0.898023 View
ENSG00000164867 NOS3 ENSG00000165731 RET H. sapiens SSL Slorth 0.896875 View
ENSG00000132646 PCNA ENSG00000165731 RET H. sapiens SSL Slorth 0.896722 View
ENSG00000150459 SAP18 ENSG00000165731 RET H. sapiens SSL Slorth 0.896535 View
ENSG00000101811 CSTF2 ENSG00000165731 RET H. sapiens SSL Slorth 0.896491 View
ENSG00000106462 EZH2 ENSG00000165731 RET H. sapiens SSL Slorth 0.894995 View
ENSG00000147065 MSN ENSG00000165731 RET H. sapiens SSL Slorth 0.894594 View
ENSG00000109971 HSPA8 ENSG00000165731 RET H. sapiens SSL Slorth 0.894553 View
ENSG00000130826 DKC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.894485 View
ENSG00000114867 EIF4G1 ENSG00000165731 RET H. sapiens SSL Slorth 0.894281 View
ENSG00000116039 ATP6V1B1 ENSG00000165731 RET H. sapiens SSL Slorth 0.894276 View
ENSG00000081189 MEF2C ENSG00000165731 RET H. sapiens SSL Slorth 0.893812 View
ENSG00000128591 FLNC ENSG00000165731 RET H. sapiens SSL Slorth 0.893128 View
ENSG00000165731 RET ENSG00000166501 PRKCB H. sapiens SSL Slorth 0.893095 View
ENSG00000116288 PARK7 ENSG00000165731 RET H. sapiens SSL Slorth 0.892395 View
ENSG00000107404 DVL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.892257 View
ENSG00000049618 ARID1B ENSG00000165731 RET H. sapiens SSL Slorth 0.892026 View
ENSG00000165731 RET ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.891817 View
ENSG00000133316 WDR74 ENSG00000165731 RET H. sapiens SSL Slorth 0.891544 View
ENSG00000047249 ATP6V1H ENSG00000165731 RET H. sapiens SSL Slorth 0.891531 View
ENSG00000068305 MEF2A ENSG00000165731 RET H. sapiens SSL Slorth 0.891461 View
ENSG00000165731 RET ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.891296 View
ENSG00000053900 ANAPC4 ENSG00000165731 RET H. sapiens SSL Slorth 0.891293 View
ENSG00000140262 TCF12 ENSG00000165731 RET H. sapiens SSL Slorth 0.890889 View
ENSG00000159216 RUNX1 ENSG00000165731 RET H. sapiens SSL Slorth 0.890732 View
ENSG00000117133 RPF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.890673 View