RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165731 RET ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.922016 View
ENSG00000141367 CLTC ENSG00000165731 RET H. sapiens SSL Slorth 0.921783 View
ENSG00000165731 RET ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.921693 View
ENSG00000141543 EIF4A3 ENSG00000165731 RET H. sapiens SSL Slorth 0.921032 View
ENSG00000130985 UBA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.921021 View
ENSG00000106299 WASL ENSG00000165731 RET H. sapiens SSL Slorth 0.920863 View
ENSG00000160294 MCM3AP ENSG00000165731 RET H. sapiens SSL Slorth 0.920042 View
ENSG00000165731 RET ENSG00000177889 UBE2N H. sapiens SSL Slorth 0.920035 View
ENSG00000123200 ZC3H13 ENSG00000165731 RET H. sapiens SSL Slorth 0.920029 View
ENSG00000165731 RET ENSG00000283094 PTEN H. sapiens SSL Slorth 0.919932 View
ENSG00000010017 RANBP9 ENSG00000165731 RET H. sapiens SSL Slorth 0.919765 View
ENSG00000165731 RET ENSG00000182578 CSF1R H. sapiens SDL Slorth 0.919563 View
ENSG00000132964 CDK8 ENSG00000165731 RET H. sapiens SSL Slorth 0.919153 View
ENSG00000102978 POLR2C ENSG00000165731 RET H. sapiens SSL Slorth 0.91911 View
ENSG00000068024 HDAC4 ENSG00000165731 RET H. sapiens SSL Slorth 0.919076 View
ENSG00000138814 PPP3CA ENSG00000165731 RET H. sapiens SSL Slorth 0.91895 View
ENSG00000079999 KEAP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.918943 View
ENSG00000165731 RET ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.918938 View
ENSG00000111875 ASF1A ENSG00000165731 RET H. sapiens SSL Slorth 0.918764 View
ENSG00000165731 RET ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.918748 View
ENSG00000108424 KPNB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.91847 View
ENSG00000039068 CDH1 ENSG00000165731 RET H. sapiens SSL Slorth 0.918008 View
ENSG00000130939 UBE4B ENSG00000165731 RET H. sapiens SSL Slorth 0.917675 View
ENSG00000165731 RET ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.917651 View
ENSG00000165731 RET ENSG00000170836 PPM1D H. sapiens SDL Slorth 0.917561 View
ENSG00000122406 RPL5 ENSG00000165731 RET H. sapiens SDL Slorth 0.917489 View
ENSG00000096384 HSP90AB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.917399 View
ENSG00000133101 CCNA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.917379 View
ENSG00000165731 RET ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.91735 View
ENSG00000165731 RET ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.917279 View
ENSG00000116473 RAP1A ENSG00000165731 RET H. sapiens SSL Slorth 0.916586 View
ENSG00000165731 RET ENSG00000182866 LCK H. sapiens SSL Slorth 0.916492 View
ENSG00000158092 NCK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.916353 View
ENSG00000108953 YWHAE ENSG00000165731 RET H. sapiens SSL Slorth 0.916311 View
ENSG00000165731 RET ENSG00000213923 CSNK1E H. sapiens SSL Slorth 0.915963 View
ENSG00000140396 NCOA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.915502 View
ENSG00000112576 CCND3 ENSG00000165731 RET H. sapiens SSL Slorth 0.915251 View
ENSG00000165731 RET ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.91524 View
ENSG00000117748 RPA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.914893 View
ENSG00000165731 RET ENSG00000167085 PHB H. sapiens SSL Slorth 0.914844 View