RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000079134 THOC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.959709 View
ENSG00000165731 RET ENSG00000204103 MAFB H. sapiens SDL Slorth 0.959462 View
ENSG00000104365 IKBKB ENSG00000165731 RET H. sapiens SSL Slorth 0.958927 View
ENSG00000118046 STK11 ENSG00000165731 RET H. sapiens SSL Slorth 0.958771 View
ENSG00000138376 BARD1 ENSG00000165731 RET H. sapiens SSL Slorth 0.95862 View
ENSG00000085511 MAP3K4 ENSG00000165731 RET H. sapiens SSL Slorth 0.958337 View
ENSG00000123374 CDK2 ENSG00000165731 RET H. sapiens SDL Slorth 0.958033 View
ENSG00000060069 CTDP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.957287 View
ENSG00000165731 RET ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.957277 View
ENSG00000131759 RARA ENSG00000165731 RET H. sapiens SSL Slorth 0.957036 View
ENSG00000140992 PDPK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.956817 View
ENSG00000137486 ARRB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.956539 View
ENSG00000154229 PRKCA ENSG00000165731 RET H. sapiens SSL Slorth 0.95653 View
ENSG00000141480 ARRB2 ENSG00000165731 RET H. sapiens SSL Slorth 0.956515 View
ENSG00000101665 SMAD7 ENSG00000165731 RET H. sapiens SSL Slorth 0.956469 View
ENSG00000070010 UFD1L ENSG00000165731 RET H. sapiens SSL Slorth 0.956261 View
ENSG00000103194 USP10 ENSG00000165731 RET H. sapiens SSL Slorth 0.956247 View
ENSG00000165731 RET ENSG00000197122 SRC H. sapiens SDL Slorth 0.95582 View
ENSG00000136238 RAC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.955782 View
ENSG00000135018 UBQLN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.955596 View
ENSG00000001626 CFTR ENSG00000165731 RET H. sapiens SSL Slorth 0.955582 View
ENSG00000134982 APC ENSG00000165731 RET H. sapiens SSL Slorth 0.955329 View
ENSG00000134853 PDGFRA ENSG00000165731 RET H. sapiens SSL Slorth 0.955067 View
ENSG00000136807 CDK9 ENSG00000165731 RET H. sapiens SSL Slorth 0.954264 View
ENSG00000093009 CDC45 ENSG00000165731 RET H. sapiens SSL Slorth 0.954166 View
ENSG00000165731 RET ENSG00000185022 MAFF H. sapiens SDL Slorth 0.953952 View
ENSG00000073111 MCM2 ENSG00000165731 RET H. sapiens SSL Slorth 0.953662 View
ENSG00000112592 TBP ENSG00000165731 RET H. sapiens SSL Slorth 0.953616 View
ENSG00000073969 NSF ENSG00000165731 RET H. sapiens SSL Slorth 0.953475 View
ENSG00000113456 RAD1 ENSG00000165731 RET H. sapiens SSL Slorth 0.95344 View
ENSG00000165731 RET ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.953137 View
ENSG00000062822 POLD1 ENSG00000165731 RET H. sapiens SSL Slorth 0.952907 View
ENSG00000082701 GSK3B ENSG00000165731 RET H. sapiens SDL Slorth 0.95276 View
ENSG00000140464 PML ENSG00000165731 RET H. sapiens SDL Slorth 0.952391 View
ENSG00000136936 XPA ENSG00000165731 RET H. sapiens SSL Slorth 0.952259 View
ENSG00000123124 WWP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.952243 View
ENSG00000084676 NCOA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.952118 View
ENSG00000148835 TAF5 ENSG00000165731 RET H. sapiens SSL Slorth 0.951466 View
ENSG00000127586 CHTF18 ENSG00000165731 RET H. sapiens SSL Slorth 0.950847 View
ENSG00000077782 FGFR1 ENSG00000165731 RET H. sapiens SDL Slorth 0.950483 View