RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000124181 PLCG1 ENSG00000165731 RET H. sapiens SDL Slorth 0.945017 View
ENSG00000112118 MCM3 ENSG00000165731 RET H. sapiens SSL Slorth 0.944688 View
ENSG00000165731 RET ENSG00000175766 EIF4E1B H. sapiens SDL Slorth 0.944322 View
ENSG00000165731 RET ENSG00000172936 MYD88 H. sapiens SDL Slorth 0.944215 View
ENSG00000103275 UBE2I ENSG00000165731 RET H. sapiens SSL Slorth 0.943499 View
ENSG00000096384 HSP90AB1 ENSG00000165731 RET H. sapiens SDL Slorth 0.943426 View
ENSG00000146648 EGFR ENSG00000165731 RET H. sapiens SSL Slorth 0.943231 View
ENSG00000004897 CDC27 ENSG00000165731 RET H. sapiens SSL Slorth 0.943135 View
ENSG00000125952 MAX ENSG00000165731 RET H. sapiens SSL Slorth 0.942779 View
ENSG00000026103 FAS ENSG00000165731 RET H. sapiens SSL Slorth 0.942724 View
ENSG00000159461 AMFR ENSG00000165731 RET H. sapiens SSL Slorth 0.94272 View
ENSG00000071564 TCF3 ENSG00000165731 RET H. sapiens SSL Slorth 0.942674 View
ENSG00000096968 JAK2 ENSG00000165731 RET H. sapiens SSL Slorth 0.941766 View
ENSG00000131759 RARA ENSG00000165731 RET H. sapiens SDL Slorth 0.941724 View
ENSG00000023445 BIRC3 ENSG00000165731 RET H. sapiens SSL Slorth 0.941703 View
ENSG00000157764 BRAF ENSG00000165731 RET H. sapiens SDL Slorth 0.941461 View
ENSG00000112062 MAPK14 ENSG00000165731 RET H. sapiens SDL Slorth 0.941379 View
ENSG00000109332 UBE2D3 ENSG00000165731 RET H. sapiens SSL Slorth 0.941267 View
ENSG00000165731 RET ENSG00000198087 CD2AP H. sapiens SDL Slorth 0.941125 View
ENSG00000121022 COPS5 ENSG00000165731 RET H. sapiens SSL Slorth 0.941082 View
ENSG00000149136 SSRP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.940919 View
ENSG00000164815 ORC5 ENSG00000165731 RET H. sapiens SSL Slorth 0.940745 View
ENSG00000101266 CSNK2A1 ENSG00000165731 RET H. sapiens SSL Slorth 0.940571 View
ENSG00000114423 CBLB ENSG00000165731 RET H. sapiens SDL Slorth 0.94055 View
ENSG00000137693 YAP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.940456 View
ENSG00000165731 RET ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.940304 View
ENSG00000067606 PRKCZ ENSG00000165731 RET H. sapiens SSL Slorth 0.940223 View
ENSG00000141646 SMAD4 ENSG00000165731 RET H. sapiens SSL Slorth 0.939967 View
ENSG00000165731 RET ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.939778 View
ENSG00000141736 ERBB2 ENSG00000165731 RET H. sapiens SDL Slorth 0.939685 View
ENSG00000145386 CCNA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.939663 View
ENSG00000108840 HDAC5 ENSG00000165731 RET H. sapiens SSL Slorth 0.939585 View
ENSG00000070831 CDC42 ENSG00000165731 RET H. sapiens SSL Slorth 0.939492 View
ENSG00000075089 ACTR6 ENSG00000165731 RET H. sapiens SSL Slorth 0.939391 View
ENSG00000140443 IGF1R ENSG00000165731 RET H. sapiens SDL Slorth 0.939286 View
ENSG00000165731 RET ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.939285 View
ENSG00000165731 RET ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.939143 View
ENSG00000149554 CHEK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.938868 View
ENSG00000138069 RAB1A ENSG00000165731 RET H. sapiens SSL Slorth 0.93867 View
ENSG00000154473 BUB3 ENSG00000165731 RET H. sapiens SSL Slorth 0.938309 View