RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165731 RET ENSG00000198400 NTRK1 H. sapiens SDL Slorth 0.938308 View
ENSG00000116044 NFE2L2 ENSG00000165731 RET H. sapiens SSL Slorth 0.938269 View
ENSG00000124164 VAPB ENSG00000165731 RET H. sapiens SSL Slorth 0.938235 View
ENSG00000066468 FGFR2 ENSG00000165731 RET H. sapiens SSL Slorth 0.938025 View
ENSG00000165731 RET ENSG00000213341 CHUK H. sapiens SSL Slorth 0.937479 View
ENSG00000070831 CDC42 ENSG00000165731 RET H. sapiens SDL Slorth 0.937031 View
ENSG00000116016 EPAS1 ENSG00000165731 RET H. sapiens SSL Slorth 0.936789 View
ENSG00000165731 RET ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.936718 View
ENSG00000100906 NFKBIA ENSG00000165731 RET H. sapiens SSL Slorth 0.936693 View
ENSG00000165025 SYK ENSG00000165731 RET H. sapiens SDL Slorth 0.936604 View
ENSG00000050820 BCAR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.936042 View
ENSG00000090372 STRN4 ENSG00000165731 RET H. sapiens SSL Slorth 0.935613 View
ENSG00000101343 CRNKL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.935532 View
ENSG00000075785 RAB7A ENSG00000165731 RET H. sapiens SSL Slorth 0.93545 View
ENSG00000128908 INO80 ENSG00000165731 RET H. sapiens SSL Slorth 0.935404 View
ENSG00000061938 TNK2 ENSG00000165731 RET H. sapiens SSL Slorth 0.935375 View
ENSG00000072518 MARK2 ENSG00000165731 RET H. sapiens SSL Slorth 0.935307 View
ENSG00000149269 PAK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.935295 View
ENSG00000165731 RET ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.935147 View
ENSG00000005339 CREBBP ENSG00000165731 RET H. sapiens SSL Slorth 0.935041 View
ENSG00000134057 CCNB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.934936 View
ENSG00000113575 PPP2CA ENSG00000165731 RET H. sapiens SSL Slorth 0.934794 View
ENSG00000128739 SNRPN ENSG00000165731 RET H. sapiens SSL Slorth 0.934553 View
ENSG00000134602 STK26 ENSG00000165731 RET H. sapiens SSL Slorth 0.934437 View
ENSG00000113575 PPP2CA ENSG00000165731 RET H. sapiens SDL Slorth 0.934418 View
ENSG00000080824 HSP90AA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.934098 View
ENSG00000165731 RET ENSG00000186868 MAPT H. sapiens SSL Slorth 0.933994 View
ENSG00000006451 RALA ENSG00000165731 RET H. sapiens SSL Slorth 0.933957 View
ENSG00000113721 PDGFRB ENSG00000165731 RET H. sapiens SDL Slorth 0.933903 View
ENSG00000165731 RET ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.933842 View
ENSG00000116473 RAP1A ENSG00000165731 RET H. sapiens SDL Slorth 0.933629 View
ENSG00000165731 RET ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.933607 View
ENSG00000164924 YWHAZ ENSG00000165731 RET H. sapiens SSL Slorth 0.933242 View
ENSG00000151247 EIF4E ENSG00000165731 RET H. sapiens SSL Slorth 0.933233 View
ENSG00000164885 CDK5 ENSG00000165731 RET H. sapiens SSL Slorth 0.933167 View
ENSG00000165731 RET ENSG00000254087 LYN H. sapiens SSL Slorth 0.932634 View
ENSG00000126261 UBA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.93253 View
ENSG00000144554 FANCD2 ENSG00000165731 RET H. sapiens SSL Slorth 0.932451 View
ENSG00000165731 RET ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.932328 View
ENSG00000115808 STRN ENSG00000165731 RET H. sapiens SSL Slorth 0.932105 View