RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135624 CCT7 ENSG00000165731 RET H. sapiens SSL Slorth 0.950356 View
ENSG00000165731 RET ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.950243 View
ENSG00000119048 UBE2B ENSG00000165731 RET H. sapiens SSL Slorth 0.950186 View
ENSG00000105810 CDK6 ENSG00000165731 RET H. sapiens SSL Slorth 0.949836 View
ENSG00000055332 EIF2AK2 ENSG00000165731 RET H. sapiens SSL Slorth 0.949722 View
ENSG00000108443 RPS6KB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.949708 View
ENSG00000147536 GINS4 ENSG00000165731 RET H. sapiens SSL Slorth 0.94969 View
ENSG00000141564 RPTOR ENSG00000165731 RET H. sapiens SSL Slorth 0.949666 View
ENSG00000064012 CASP8 ENSG00000165731 RET H. sapiens SSL Slorth 0.949549 View
ENSG00000110395 CBL ENSG00000165731 RET H. sapiens SSL Slorth 0.949524 View
ENSG00000119541 VPS4B ENSG00000165731 RET H. sapiens SSL Slorth 0.949465 View
ENSG00000165527 ARF6 ENSG00000165731 RET H. sapiens SSL Slorth 0.949178 View
ENSG00000091831 ESR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.948803 View
ENSG00000165731 RET ENSG00000169032 MAP2K1 H. sapiens SDL Slorth 0.94852 View
ENSG00000123374 CDK2 ENSG00000165731 RET H. sapiens SSL Slorth 0.948508 View
ENSG00000078747 ITCH ENSG00000165731 RET H. sapiens SSL Slorth 0.948163 View
ENSG00000078140 UBE2K ENSG00000165731 RET H. sapiens SSL Slorth 0.948129 View
ENSG00000128052 KDR ENSG00000165731 RET H. sapiens SDL Slorth 0.948013 View
ENSG00000117399 CDC20 ENSG00000165731 RET H. sapiens SSL Slorth 0.947925 View
ENSG00000104365 IKBKB ENSG00000165731 RET H. sapiens SDL Slorth 0.947762 View
ENSG00000075624 ACTB ENSG00000165731 RET H. sapiens SSL Slorth 0.947653 View
ENSG00000010810 FYN ENSG00000165731 RET H. sapiens SDL Slorth 0.947278 View
ENSG00000135341 MAP3K7 ENSG00000165731 RET H. sapiens SSL Slorth 0.946982 View
ENSG00000136518 ACTL6A ENSG00000165731 RET H. sapiens SSL Slorth 0.946863 View
ENSG00000089159 PXN ENSG00000165731 RET H. sapiens SDL Slorth 0.946595 View
ENSG00000147010 SH3KBP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.946441 View
ENSG00000118260 CREB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.946369 View
ENSG00000100603 SNW1 ENSG00000165731 RET H. sapiens SSL Slorth 0.946275 View
ENSG00000127511 SIN3B ENSG00000165731 RET H. sapiens SSL Slorth 0.946205 View
ENSG00000163932 PRKCD ENSG00000165731 RET H. sapiens SSL Slorth 0.946108 View
ENSG00000106290 TAF6 ENSG00000165731 RET H. sapiens SSL Slorth 0.946014 View
ENSG00000112531 QKI ENSG00000165731 RET H. sapiens SSL Slorth 0.945931 View
ENSG00000159692 CTBP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.945882 View
ENSG00000114423 CBLB ENSG00000165731 RET H. sapiens SSL Slorth 0.945823 View
ENSG00000051180 RAD51 ENSG00000165731 RET H. sapiens SSL Slorth 0.945805 View
ENSG00000165731 RET ENSG00000178997 EXD1 H. sapiens SDL Slorth 0.945755 View
ENSG00000164305 CASP3 ENSG00000165731 RET H. sapiens SDL Slorth 0.945471 View
ENSG00000165280 VCP ENSG00000165731 RET H. sapiens SSL Slorth 0.94528 View
ENSG00000112062 MAPK14 ENSG00000165731 RET H. sapiens SSL Slorth 0.945112 View
ENSG00000094804 CDC6 ENSG00000165731 RET H. sapiens SSL Slorth 0.945032 View