KDR

ENSG00000128052 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0051879 Hsp90 protein binding

Drugs

Drug name Description
AXITINIB Vascular endothelial growth factor receptor inhibitor
CABOZANTINIB
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
RAMUCIRUMAB Vascular endothelial growth factor receptor 2 inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
NSCLC
angiosarcoma
melanoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000128052 KDR ENSG00000141510 TP53 H. sapiens SSL BioGRID 1.0 View
ENSG00000012048 BRCA1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.990202 View
ENSG00000100393 EP300 ENSG00000128052 KDR H. sapiens SDL Slorth 0.989524 View
ENSG00000091831 ESR1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.986886 View
ENSG00000005339 CREBBP ENSG00000128052 KDR H. sapiens SDL Slorth 0.986617 View
ENSG00000116478 HDAC1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.985648 View
ENSG00000080824 HSP90AA1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.985033 View
ENSG00000100030 MAPK1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.983661 View
ENSG00000128052 KDR ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.981289 View
ENSG00000110395 CBL ENSG00000128052 KDR H. sapiens SDL Slorth 0.98096 View
ENSG00000128052 KDR ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.980898 View
ENSG00000128052 KDR ENSG00000165409 TSHR H. sapiens SDL Slorth 0.979146 View
ENSG00000101266 CSNK2A1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.978528 View
ENSG00000128052 KDR ENSG00000130766 SESN2 H. sapiens SDL Slorth 0.977546 View
ENSG00000128052 KDR ENSG00000150991 UBC H. sapiens SDL Slorth 0.977165 View
ENSG00000128052 KDR ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.975703 View
ENSG00000128052 KDR ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.975203 View
ENSG00000128052 KDR ENSG00000135723 FHOD1 H. sapiens SDL Slorth 0.974826 View
ENSG00000128052 KDR ENSG00000144668 ITGA9 H. sapiens SDL Slorth 0.974544 View
ENSG00000128052 KDR ENSG00000157601 MX1 H. sapiens SDL Slorth 0.974373 View
ENSG00000128052 KDR ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.974172 View
ENSG00000128052 KDR ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.974162 View
ENSG00000128052 KDR ENSG00000189067 LITAF H. sapiens SDL Slorth 0.974038 View
ENSG00000101266 CSNK2A1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.973769 View
ENSG00000128052 KDR ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.973512 View
ENSG00000128052 KDR ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.973196 View
ENSG00000128052 KDR ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.972069 View
ENSG00000128052 KDR ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.971946 View
ENSG00000128052 KDR ENSG00000138756 BMP2K H. sapiens SDL Slorth 0.971034 View
ENSG00000128052 KDR ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.971032 View
ENSG00000128052 KDR ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.97046 View
ENSG00000128052 KDR ENSG00000182511 FES H. sapiens SDL Slorth 0.970373 View
ENSG00000128052 KDR ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.969744 View
ENSG00000121022 COPS5 ENSG00000128052 KDR H. sapiens SSL Slorth 0.969732 View
ENSG00000116030 SUMO1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.969669 View
ENSG00000128052 KDR ENSG00000135090 TAOK3 H. sapiens SDL Slorth 0.969497 View
ENSG00000128052 KDR ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.969396 View
ENSG00000128052 KDR ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.96909 View
ENSG00000128052 KDR ENSG00000160145 KALRN H. sapiens SDL Slorth 0.968822 View
ENSG00000128052 KDR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.968793 View