KDR

ENSG00000128052 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0051879 Hsp90 protein binding

Drugs

Drug name Description
AXITINIB Vascular endothelial growth factor receptor inhibitor
CABOZANTINIB
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
RAMUCIRUMAB Vascular endothelial growth factor receptor 2 inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
NSCLC
angiosarcoma
melanoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000128052 KDR ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.960695 View
ENSG00000128052 KDR ENSG00000143776 CDC42BPA H. sapiens SDL Slorth 0.960582 View
ENSG00000070010 UFD1L ENSG00000128052 KDR H. sapiens SSL Slorth 0.960578 View
ENSG00000128052 KDR ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.96007 View
ENSG00000108443 RPS6KB1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.959703 View
ENSG00000128052 KDR ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.959493 View
ENSG00000128052 KDR ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959257 View
ENSG00000004700 RECQL ENSG00000128052 KDR H. sapiens SSL Slorth 0.959244 View
ENSG00000010810 FYN ENSG00000128052 KDR H. sapiens SSL Slorth 0.959233 View
ENSG00000117399 CDC20 ENSG00000128052 KDR H. sapiens SSL Slorth 0.959092 View
ENSG00000128052 KDR ENSG00000169083 AR H. sapiens SDL Slorth 0.959032 View
ENSG00000128052 KDR ENSG00000135597 REPS1 H. sapiens SDL Slorth 0.958922 View
ENSG00000111276 CDKN1B ENSG00000128052 KDR H. sapiens SSL Slorth 0.958878 View
ENSG00000010810 FYN ENSG00000128052 KDR H. sapiens SDL Slorth 0.958336 View
ENSG00000101868 POLA1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.958237 View
ENSG00000078747 ITCH ENSG00000128052 KDR H. sapiens SSL Slorth 0.958187 View
ENSG00000109971 HSPA8 ENSG00000128052 KDR H. sapiens SSL Slorth 0.958052 View
ENSG00000104365 IKBKB ENSG00000128052 KDR H. sapiens SSL Slorth 0.957857 View
ENSG00000128052 KDR ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.957797 View
ENSG00000121879 PIK3CA ENSG00000128052 KDR H. sapiens SSL Slorth 0.957321 View
ENSG00000128052 KDR ENSG00000155846 PPARGC1B H. sapiens SDL Slorth 0.957194 View
ENSG00000128052 KDR ENSG00000152284 TCF7L1 H. sapiens SDL Slorth 0.957106 View
ENSG00000105976 MET ENSG00000128052 KDR H. sapiens SDL Slorth 0.956862 View
ENSG00000097046 CDC7 ENSG00000128052 KDR H. sapiens SSL Slorth 0.956735 View
ENSG00000106799 TGFBR1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.956167 View
ENSG00000001626 CFTR ENSG00000128052 KDR H. sapiens SSL Slorth 0.955951 View
ENSG00000128052 KDR ENSG00000146094 DOK3 H. sapiens SDL Slorth 0.955531 View
ENSG00000128052 KDR ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.9552 View
ENSG00000105974 CAV1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.95477 View
ENSG00000118046 STK11 ENSG00000128052 KDR H. sapiens SSL Slorth 0.95477 View
ENSG00000110395 CBL ENSG00000128052 KDR H. sapiens SSL Slorth 0.954385 View
ENSG00000128052 KDR ENSG00000131400 NAPSA H. sapiens SDL Slorth 0.954365 View
ENSG00000128052 KDR ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.953747 View
ENSG00000096968 JAK2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.953299 View
ENSG00000128052 KDR ENSG00000213585 VDAC1 H. sapiens SDL Slorth 0.953185 View
ENSG00000128052 KDR ENSG00000136237 RAPGEF5 H. sapiens SDL Slorth 0.953085 View
ENSG00000109906 ZBTB16 ENSG00000128052 KDR H. sapiens SSL Slorth 0.953013 View
ENSG00000104365 IKBKB ENSG00000128052 KDR H. sapiens SDL Slorth 0.952962 View
ENSG00000128052 KDR ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.952237 View
ENSG00000111875 ASF1A ENSG00000128052 KDR H. sapiens SSL Slorth 0.952035 View