KDR

ENSG00000128052 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0051879 Hsp90 protein binding

Drugs

Drug name Description
AXITINIB Vascular endothelial growth factor receptor inhibitor
CABOZANTINIB
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
RAMUCIRUMAB Vascular endothelial growth factor receptor 2 inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
NSCLC
angiosarcoma
melanoma

Orthologs

Gene Organism
Pvr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000112118 MCM3 ENSG00000128052 KDR H. sapiens SSL Slorth 0.94238 View
ENSG00000065559 MAP2K4 ENSG00000128052 KDR H. sapiens SSL Slorth 0.942364 View
ENSG00000124762 CDKN1A ENSG00000128052 KDR H. sapiens SDL Slorth 0.941988 View
ENSG00000128052 KDR ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.941981 View
ENSG00000100603 SNW1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.941975 View
ENSG00000128052 KDR ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.94176 View
ENSG00000091831 ESR1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.941672 View
ENSG00000067560 RHOA ENSG00000128052 KDR H. sapiens SSL Slorth 0.941597 View
ENSG00000128052 KDR ENSG00000185345 PARK2 H. sapiens SDL Slorth 0.941532 View
ENSG00000100644 HIF1A ENSG00000128052 KDR H. sapiens SDL Slorth 0.941523 View
ENSG00000110048 OSBP ENSG00000128052 KDR H. sapiens SDL Slorth 0.941326 View
ENSG00000128052 KDR ENSG00000176720 BOK H. sapiens SDL Slorth 0.941284 View
ENSG00000128052 KDR ENSG00000254087 LYN H. sapiens SDL Slorth 0.941244 View
ENSG00000005339 CREBBP ENSG00000128052 KDR H. sapiens SSL Slorth 0.940653 View
ENSG00000051180 RAD51 ENSG00000128052 KDR H. sapiens SSL Slorth 0.940532 View
ENSG00000108840 HDAC5 ENSG00000128052 KDR H. sapiens SSL Slorth 0.940448 View
ENSG00000124181 PLCG1 ENSG00000128052 KDR H. sapiens SDL Slorth 0.940253 View
ENSG00000074319 TSG101 ENSG00000128052 KDR H. sapiens SSL Slorth 0.94015 View
ENSG00000119541 VPS4B ENSG00000128052 KDR H. sapiens SSL Slorth 0.940121 View
ENSG00000106290 TAF6 ENSG00000128052 KDR H. sapiens SSL Slorth 0.939939 View
ENSG00000128052 KDR ENSG00000163558 PRKCI H. sapiens SDL Slorth 0.939709 View
ENSG00000116044 NFE2L2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.939641 View
ENSG00000080815 PSEN1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.93964 View
ENSG00000075624 ACTB ENSG00000128052 KDR H. sapiens SSL Slorth 0.939609 View
ENSG00000010671 BTK ENSG00000128052 KDR H. sapiens SDL Slorth 0.939469 View
ENSG00000115942 ORC2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.939297 View
ENSG00000106355 LSM5 ENSG00000128052 KDR H. sapiens SSL Slorth 0.939129 View
ENSG00000128052 KDR ENSG00000173402 DAG1 H. sapiens SDL Slorth 0.939054 View
ENSG00000128052 KDR ENSG00000170315 UBB H. sapiens SDL Slorth 0.938285 View
ENSG00000082898 XPO1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.938095 View
ENSG00000044574 HSPA5 ENSG00000128052 KDR H. sapiens SSL Slorth 0.937998 View
ENSG00000114423 CBLB ENSG00000128052 KDR H. sapiens SSL Slorth 0.937733 View
ENSG00000114742 WDR48 ENSG00000128052 KDR H. sapiens SSL Slorth 0.937329 View
ENSG00000101412 E2F1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.937271 View
ENSG00000067560 RHOA ENSG00000128052 KDR H. sapiens SDL Slorth 0.937009 View
ENSG00000124181 PLCG1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.936749 View
ENSG00000072518 MARK2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.936333 View
ENSG00000071564 TCF3 ENSG00000128052 KDR H. sapiens SSL Slorth 0.936148 View
ENSG00000103197 TSC2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.936015 View
ENSG00000080824 HSP90AA1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.935949 View