RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000106263 EIF3B ENSG00000165731 RET H. sapiens SSL Slorth 0.914749 View
ENSG00000114302 PRKAR2A ENSG00000165731 RET H. sapiens SSL Slorth 0.91474 View
ENSG00000156052 GNAQ ENSG00000165731 RET H. sapiens SSL Slorth 0.914722 View
ENSG00000165731 RET ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.914568 View
ENSG00000165731 RET ENSG00000198793 MTOR H. sapiens SDL Slorth 0.914462 View
ENSG00000096968 JAK2 ENSG00000165731 RET H. sapiens SDL Slorth 0.914197 View
ENSG00000165731 RET ENSG00000177606 JUN H. sapiens SDL Slorth 0.913813 View
ENSG00000165731 RET ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.913781 View
ENSG00000010671 BTK ENSG00000165731 RET H. sapiens SDL Slorth 0.913484 View
ENSG00000062650 WAPL ENSG00000165731 RET H. sapiens SSL Slorth 0.912909 View
ENSG00000139618 BRCA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.912748 View
ENSG00000124486 USP9X ENSG00000165731 RET H. sapiens SSL Slorth 0.912565 View
ENSG00000080815 PSEN1 ENSG00000165731 RET H. sapiens SDL Slorth 0.912513 View
ENSG00000099804 CDC34 ENSG00000165731 RET H. sapiens SSL Slorth 0.912445 View
ENSG00000165731 RET ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.912394 View
ENSG00000165731 RET ENSG00000254087 LYN H. sapiens SDL Slorth 0.912082 View
ENSG00000165731 RET ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.91186 View
ENSG00000103126 AXIN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.911727 View
ENSG00000165731 RET ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.911658 View
ENSG00000135250 SRPK2 ENSG00000165731 RET H. sapiens SSL Slorth 0.911463 View
ENSG00000165731 RET ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.91146 View
ENSG00000124813 RUNX2 ENSG00000165731 RET H. sapiens SSL Slorth 0.911403 View
ENSG00000035403 VCL ENSG00000165731 RET H. sapiens SSL Slorth 0.911362 View
ENSG00000165119 HNRNPK ENSG00000165731 RET H. sapiens SDL Slorth 0.911238 View
ENSG00000163485 ADORA1 ENSG00000165731 RET H. sapiens SDL Slorth 0.911157 View
ENSG00000134308 YWHAQ ENSG00000165731 RET H. sapiens SSL Slorth 0.911119 View
ENSG00000140538 NTRK3 ENSG00000165731 RET H. sapiens SDL Slorth 0.910932 View
ENSG00000136875 PRPF4 ENSG00000165731 RET H. sapiens SSL Slorth 0.910799 View
ENSG00000141503 MINK1 ENSG00000165731 RET H. sapiens SDL Slorth 0.910418 View
ENSG00000079102 RUNX1T1 ENSG00000165731 RET H. sapiens SSL Slorth 0.910308 View
ENSG00000165731 RET ENSG00000167461 RAB8A H. sapiens SDL Slorth 0.910305 View
ENSG00000165731 RET ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.910179 View
ENSG00000155974 GRIP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.910145 View
ENSG00000165731 RET ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.90965 View
ENSG00000113712 CSNK1A1 ENSG00000165731 RET H. sapiens SSL Slorth 0.90956 View
ENSG00000165731 RET ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.909421 View
ENSG00000102882 MAPK3 ENSG00000165731 RET H. sapiens SDL Slorth 0.909411 View
ENSG00000109062 SLC9A3R1 ENSG00000165731 RET H. sapiens SDL Slorth 0.909235 View
ENSG00000070950 RAD18 ENSG00000165731 RET H. sapiens SSL Slorth 0.908942 View
ENSG00000116604 MEF2D ENSG00000165731 RET H. sapiens SSL Slorth 0.908781 View