LCK

ENSG00000182866 - H. sapiens

Pathways

Go term Description
GO:0001948 glycoprotein binding
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016301 kinase activity
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0042169 SH2 domain binding
GO:0042609 CD4 receptor binding
GO:0042610 CD8 receptor binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0051117 ATPase binding

Drugs

Drug name Description
DASATINIB Tyrosine-protein kinase ABL inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
T-ALL

Orthologs

Gene Organism
Src64B D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000182866 LCK ENSG00000101213 PTK6 H. sapiens SSL BioGRID 1.0 View
ENSG00000135409 AMHR2 ENSG00000182866 LCK H. sapiens SSL BioGRID 1.0 View
ENSG00000148660 CAMK2G ENSG00000182866 LCK H. sapiens SSL BioGRID 1.0 View
ENSG00000100122 CRYBB1 ENSG00000182866 LCK H. sapiens SSL BioGRID 1.0 View
ENSG00000196411 EPHB4 ENSG00000182866 LCK H. sapiens SSL BioGRID 1.0 View
ENSG00000139626 ITGB7 ENSG00000182866 LCK H. sapiens SSL BioGRID 1.0 View
ENSG00000182866 LCK ENSG00000213903 LTB4R H. sapiens SSL BioGRID 1.0 View
ENSG00000182866 LCK ENSG00000076984 MAP2K7 H. sapiens SSL BioGRID 1.0 View
ENSG00000182866 LCK ENSG00000107968 MAP3K8 H. sapiens SSL BioGRID 1.0 View
ENSG00000182866 LCK ENSG00000188130 MAPK12 H. sapiens SSL BioGRID 1.0 View
ENSG00000182866 LCK ENSG00000009724 MASP2 H. sapiens SSL BioGRID 1.0 View
ENSG00000182866 LCK ENSG00000007171 NOS2 H. sapiens SSL BioGRID 1.0 View
ENSG00000182866 LCK ENSG00000133056 PIK3C2B H. sapiens SSL BioGRID 1.0 View
ENSG00000150991 UBC ENSG00000182866 LCK H. sapiens SDL Slorth 0.986632 View
ENSG00000166548 TK2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.984171 View
ENSG00000163485 ADORA1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.984168 View
ENSG00000012048 BRCA1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.984036 View
ENSG00000132386 SERPINF1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.983968 View
ENSG00000067829 IDH3G ENSG00000182866 LCK H. sapiens SDL Slorth 0.983869 View
ENSG00000102996 MMP15 ENSG00000182866 LCK H. sapiens SDL Slorth 0.983651 View
ENSG00000129245 FXR2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.983558 View
ENSG00000080824 HSP90AA1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.983508 View
ENSG00000149968 MMP3 ENSG00000182866 LCK H. sapiens SDL Slorth 0.983458 View
ENSG00000095397 WHRN ENSG00000182866 LCK H. sapiens SDL Slorth 0.983148 View
ENSG00000146232 NFKBIE ENSG00000182866 LCK H. sapiens SDL Slorth 0.983004 View
ENSG00000107282 APBA1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.982855 View
ENSG00000105737 GRIK5 ENSG00000182866 LCK H. sapiens SDL Slorth 0.982806 View
ENSG00000133124 IRS4 ENSG00000182866 LCK H. sapiens SDL Slorth 0.982615 View
ENSG00000106346 USP42 ENSG00000182866 LCK H. sapiens SDL Slorth 0.982293 View
ENSG00000182866 LCK ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.982186 View
ENSG00000182866 LCK ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.98215 View
ENSG00000110048 OSBP ENSG00000182866 LCK H. sapiens SDL Slorth 0.982078 View
ENSG00000104140 RHOV ENSG00000182866 LCK H. sapiens SDL Slorth 0.982045 View
ENSG00000130703 OSBPL2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.982021 View
ENSG00000176894 PXMP2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.982003 View
ENSG00000100372 SLC25A17 ENSG00000182866 LCK H. sapiens SDL Slorth 0.982003 View
ENSG00000079156 OSBPL6 ENSG00000182866 LCK H. sapiens SDL Slorth 0.981965 View
ENSG00000100982 PCIF1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.981948 View
ENSG00000137073 UBAP2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.981948 View
ENSG00000182197 EXT1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.981948 View