LCK

ENSG00000182866 - H. sapiens

Pathways

Go term Description
GO:0001948 glycoprotein binding
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016301 kinase activity
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0042169 SH2 domain binding
GO:0042609 CD4 receptor binding
GO:0042610 CD8 receptor binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0051117 ATPase binding

Drugs

Drug name Description
DASATINIB Tyrosine-protein kinase ABL inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
T-ALL

Orthologs

Gene Organism
Src64B D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143033 MTF2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.97031 View
ENSG00000139631 CSAD ENSG00000182866 LCK H. sapiens SDL Slorth 0.970264 View
ENSG00000175518 UBQLNL ENSG00000182866 LCK H. sapiens SDL Slorth 0.970264 View
ENSG00000135723 FHOD1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.970261 View
ENSG00000182810 DDX28 ENSG00000182866 LCK H. sapiens SDL Slorth 0.970219 View
ENSG00000110395 CBL ENSG00000182866 LCK H. sapiens SDL Slorth 0.970133 View
ENSG00000004848 ARX ENSG00000182866 LCK H. sapiens SDL Slorth 0.969959 View
ENSG00000148429 USP6NL ENSG00000182866 LCK H. sapiens SDL Slorth 0.969818 View
ENSG00000123094 RASSF8 ENSG00000182866 LCK H. sapiens SDL Slorth 0.96972 View
ENSG00000011454 RABGAP1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.969703 View
ENSG00000182866 LCK ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.969542 View
ENSG00000182866 LCK ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.969456 View
ENSG00000144644 GADL1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.969341 View
ENSG00000180900 SCRIB ENSG00000182866 LCK H. sapiens SDL Slorth 0.969326 View
ENSG00000110330 BIRC2 ENSG00000182866 LCK H. sapiens SSL Slorth 0.969192 View
ENSG00000074219 TEAD2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.969077 View
ENSG00000157764 BRAF ENSG00000182866 LCK H. sapiens SSL Slorth 0.968868 View
ENSG00000108953 YWHAE ENSG00000182866 LCK H. sapiens SSL Slorth 0.968866 View
ENSG00000170836 PPM1D ENSG00000182866 LCK H. sapiens SDL Slorth 0.968861 View
ENSG00000132466 ANKRD17 ENSG00000182866 LCK H. sapiens SDL Slorth 0.968573 View
ENSG00000005882 PDK2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.968546 View
ENSG00000118900 UBN1 ENSG00000182866 LCK H. sapiens SDL Slorth 0.968546 View
ENSG00000136750 GAD2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.9685 View
ENSG00000080815 PSEN1 ENSG00000182866 LCK H. sapiens SSL Slorth 0.968379 View
ENSG00000007264 MATK ENSG00000182866 LCK H. sapiens SDL Slorth 0.968213 View
ENSG00000160145 KALRN ENSG00000182866 LCK H. sapiens SDL Slorth 0.967963 View
ENSG00000128245 YWHAH ENSG00000182866 LCK H. sapiens SSL Slorth 0.96794 View
ENSG00000165115 KIF27 ENSG00000182866 LCK H. sapiens SDL Slorth 0.967796 View
ENSG00000141480 ARRB2 ENSG00000182866 LCK H. sapiens SSL Slorth 0.967651 View
ENSG00000130766 SESN2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.967594 View
ENSG00000085999 RAD54L ENSG00000182866 LCK H. sapiens SDL Slorth 0.967593 View
ENSG00000182866 LCK ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.967575 View
ENSG00000146701 MDH2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.967515 View
ENSG00000135312 HTR1B ENSG00000182866 LCK H. sapiens SDL Slorth 0.967511 View
ENSG00000148400 NOTCH1 ENSG00000182866 LCK H. sapiens SSL Slorth 0.967428 View
ENSG00000125810 CD93 ENSG00000182866 LCK H. sapiens SDL Slorth 0.967354 View
ENSG00000167552 TUBA1A ENSG00000182866 LCK H. sapiens SSL Slorth 0.966975 View
ENSG00000104129 DNAJC17 ENSG00000182866 LCK H. sapiens SDL Slorth 0.966856 View
ENSG00000131941 RHPN2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.966823 View
ENSG00000165238 WNK2 ENSG00000182866 LCK H. sapiens SDL Slorth 0.966537 View