LCK

ENSG00000182866 - H. sapiens

Pathways

Go term Description
GO:0001948 glycoprotein binding
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016301 kinase activity
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0042169 SH2 domain binding
GO:0042609 CD4 receptor binding
GO:0042610 CD8 receptor binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0051117 ATPase binding

Drugs

Drug name Description
DASATINIB Tyrosine-protein kinase ABL inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
T-ALL

Orthologs

Gene Organism
Src64B D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000182866 LCK ENSG00000188612 SUMO2 H. sapiens SSL Slorth 0.750216 View
ENSG00000070018 LRP6 ENSG00000182866 LCK H. sapiens SSL Slorth 0.750096 View
ENSG00000138107 ACTR1A ENSG00000182866 LCK H. sapiens SSL Slorth 0.750034 View