LRP6

ENSG00000070018 - H. sapiens

Pathways

Go term Description
GO:0005041 low-density lipoprotein receptor activity
GO:0005102 receptor binding
GO:0005109 frizzled binding
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
GO:0019210 kinase inhibitor activity
GO:0019534 toxin transporter activity
GO:0034185 apolipoprotein binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042813 Wnt-activated receptor activity
GO:0071936 coreceptor activity involved in Wnt signaling pathway
GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
arr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000070018 LRP6 ENSG00000150991 UBC H. sapiens SDL Slorth 0.976602 View
ENSG00000012048 BRCA1 ENSG00000070018 LRP6 H. sapiens SDL Slorth 0.966206 View
ENSG00000070018 LRP6 ENSG00000082701 GSK3B H. sapiens SDL Slorth 0.959109 View
ENSG00000070018 LRP6 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.958106 View
ENSG00000070018 LRP6 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.95486 View
ENSG00000070018 LRP6 ENSG00000170315 UBB H. sapiens SDL Slorth 0.948868 View
ENSG00000070018 LRP6 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.944378 View
ENSG00000070018 LRP6 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.94153 View
ENSG00000070018 LRP6 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.93815 View
ENSG00000004700 RECQL ENSG00000070018 LRP6 H. sapiens SSL Slorth 0.928581 View
ENSG00000070018 LRP6 ENSG00000197122 SRC H. sapiens SDL Slorth 0.917775 View
ENSG00000070018 LRP6 ENSG00000080824 HSP90AA1 H. sapiens SDL Slorth 0.916609 View
ENSG00000070018 LRP6 ENSG00000100030 MAPK1 H. sapiens SDL Slorth 0.907255 View
ENSG00000070010 UFD1L ENSG00000070018 LRP6 H. sapiens SSL Slorth 0.904661 View
ENSG00000005339 CREBBP ENSG00000070018 LRP6 H. sapiens SDL Slorth 0.9044 View
ENSG00000070018 LRP6 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.903289 View
ENSG00000070018 LRP6 ENSG00000101266 CSNK2A1 H. sapiens SDL Slorth 0.901948 View
ENSG00000070018 LRP6 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.900189 View
ENSG00000062822 POLD1 ENSG00000070018 LRP6 H. sapiens SSL Slorth 0.89657 View
ENSG00000070018 LRP6 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.868111 View
ENSG00000070018 LRP6 ENSG00000106211 HSPB1 H. sapiens SSL Slorth 0.860635 View
ENSG00000012048 BRCA1 ENSG00000070018 LRP6 H. sapiens SSL Slorth 0.85863 View
ENSG00000070018 LRP6 ENSG00000074319 TSG101 H. sapiens SSL Slorth 0.857395 View
ENSG00000070018 LRP6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.85539 View
ENSG00000070018 LRP6 ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.848691 View
ENSG00000070018 LRP6 ENSG00000085832 EPS15 H. sapiens SSL Slorth 0.845686 View
ENSG00000070018 LRP6 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.838207 View
ENSG00000070018 LRP6 ENSG00000150093 ITGB1 H. sapiens SSL Slorth 0.833821 View
ENSG00000070018 LRP6 ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.832788 View
ENSG00000070018 LRP6 ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.830512 View
ENSG00000070018 LRP6 ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.830194 View
ENSG00000070018 LRP6 ENSG00000127022 CANX H. sapiens SSL Slorth 0.828696 View
ENSG00000070018 LRP6 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.825088 View
ENSG00000070018 LRP6 ENSG00000108443 RPS6KB1 H. sapiens SSL Slorth 0.823463 View
ENSG00000070018 LRP6 ENSG00000185359 HGS H. sapiens SSL Slorth 0.821979 View
ENSG00000070018 LRP6 ENSG00000106799 TGFBR1 H. sapiens SSL Slorth 0.821852 View
ENSG00000070018 LRP6 ENSG00000105976 MET H. sapiens SSL Slorth 0.821313 View
ENSG00000070018 LRP6 ENSG00000254087 LYN H. sapiens SSL Slorth 0.820149 View
ENSG00000070018 LRP6 ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.819942 View
ENSG00000070018 LRP6 ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.817905 View