RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165731 RET ENSG00000186575 NF2 H. sapiens SSL Slorth 0.851076 View
ENSG00000136152 COG3 ENSG00000165731 RET H. sapiens SSL Slorth 0.850897 View
ENSG00000143256 PFDN2 ENSG00000165731 RET H. sapiens SSL Slorth 0.850823 View
ENSG00000133627 ACTR3B ENSG00000165731 RET H. sapiens SSL Slorth 0.850789 View
ENSG00000076242 MLH1 ENSG00000165731 RET H. sapiens SSL Slorth 0.850486 View
ENSG00000131475 VPS25 ENSG00000165731 RET H. sapiens SSL Slorth 0.849657 View
ENSG00000107651 SEC23IP ENSG00000165731 RET H. sapiens SSL Slorth 0.849551 View
ENSG00000123349 PFDN5 ENSG00000165731 RET H. sapiens SSL Slorth 0.849077 View
ENSG00000114573 ATP6V1A ENSG00000165731 RET H. sapiens SSL Slorth 0.848941 View
ENSG00000092847 AGO1 ENSG00000165731 RET H. sapiens SSL Slorth 0.848652 View
ENSG00000035928 RFC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.848601 View
ENSG00000165731 RET ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.848265 View
ENSG00000130479 MAP1S ENSG00000165731 RET H. sapiens SSL Slorth 0.848127 View
ENSG00000124788 ATXN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.84793 View
ENSG00000158169 FANCC ENSG00000165731 RET H. sapiens SSL Slorth 0.847887 View
ENSG00000079950 STX7 ENSG00000165731 RET H. sapiens SSL Slorth 0.847632 View
ENSG00000165731 RET ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.847565 View
ENSG00000142655 PEX14 ENSG00000165731 RET H. sapiens SSL Slorth 0.847442 View
ENSG00000057608 GDI2 ENSG00000165731 RET H. sapiens SSL Slorth 0.847373 View
ENSG00000147133 TAF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.847216 View
ENSG00000112715 VEGFA ENSG00000165731 RET H. sapiens SSL Slorth 0.846934 View
ENSG00000006715 VPS41 ENSG00000165731 RET H. sapiens SSL Slorth 0.846802 View
ENSG00000118689 FOXO3 ENSG00000165731 RET H. sapiens SSL Slorth 0.846461 View
ENSG00000113013 HSPA9 ENSG00000165731 RET H. sapiens SSL Slorth 0.845971 View
ENSG00000123737 EXOSC9 ENSG00000165731 RET H. sapiens SSL Slorth 0.845944 View
ENSG00000139842 CUL4A ENSG00000165731 RET H. sapiens SSL Slorth 0.845917 View
ENSG00000108384 RAD51C ENSG00000165731 RET H. sapiens SSL Slorth 0.845698 View
ENSG00000008128 CDK11A ENSG00000165731 RET H. sapiens SSL Slorth 0.845628 View
ENSG00000100227 POLDIP3 ENSG00000165731 RET H. sapiens SSL Slorth 0.84544 View
ENSG00000165731 RET ENSG00000180370 PAK2 H. sapiens SSL Slorth 0.845282 View
ENSG00000088832 FKBP1A ENSG00000165731 RET H. sapiens SSL Slorth 0.843847 View
ENSG00000086065 CHMP5 ENSG00000165731 RET H. sapiens SSL Slorth 0.843767 View
ENSG00000165731 RET ENSG00000179262 RAD23A H. sapiens SSL Slorth 0.843587 View
ENSG00000165731 RET ENSG00000166598 HSP90B1 H. sapiens SSL Slorth 0.84316 View
ENSG00000165731 RET ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.843021 View
ENSG00000147162 OGT ENSG00000165731 RET H. sapiens SSL Slorth 0.842697 View
ENSG00000165731 RET ENSG00000168556 ING2 H. sapiens SSL Slorth 0.842591 View
ENSG00000134684 YARS ENSG00000165731 RET H. sapiens SSL Slorth 0.842342 View
ENSG00000165731 RET ENSG00000178950 GAK H. sapiens SSL Slorth 0.842308 View
ENSG00000086598 TMED2 ENSG00000165731 RET H. sapiens SSL Slorth 0.842306 View