RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000099956 SMARCB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.842028 View
ENSG00000101751 POLI ENSG00000165731 RET H. sapiens SSL Slorth 0.841709 View
ENSG00000165731 RET ENSG00000172053 QARS H. sapiens SSL Slorth 0.841565 View
ENSG00000136504 KAT7 ENSG00000165731 RET H. sapiens SSL Slorth 0.841469 View
ENSG00000164134 NAA15 ENSG00000165731 RET H. sapiens SSL Slorth 0.841406 View
ENSG00000125971 DYNLRB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.8412 View
ENSG00000101197 BIRC7 ENSG00000165731 RET H. sapiens SSL Slorth 0.841173 View
ENSG00000023287 RB1CC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.841016 View
ENSG00000165731 RET ENSG00000166197 NOLC1 H. sapiens SSL Slorth 0.840873 View
ENSG00000165731 RET ENSG00000168283 BMI1 H. sapiens SSL Slorth 0.840706 View
ENSG00000089289 IGBP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.840441 View
ENSG00000079785 DDX1 ENSG00000165731 RET H. sapiens SSL Slorth 0.840249 View
ENSG00000096401 CDC5L ENSG00000165731 RET H. sapiens SSL Slorth 0.840247 View
ENSG00000067225 PKM ENSG00000165731 RET H. sapiens SSL Slorth 0.839979 View
ENSG00000115816 CEBPZ ENSG00000165731 RET H. sapiens SSL Slorth 0.839874 View
ENSG00000108561 C1QBP ENSG00000165731 RET H. sapiens SSL Slorth 0.839758 View
ENSG00000019995 ZRANB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.839102 View
ENSG00000104969 SGTA ENSG00000165731 RET H. sapiens SSL Slorth 0.838941 View
ENSG00000113810 SMC4 ENSG00000165731 RET H. sapiens SSL Slorth 0.838642 View
ENSG00000107643 MAPK8 ENSG00000165731 RET H. sapiens SSL Slorth 0.83858 View
ENSG00000139719 VPS33A ENSG00000165731 RET H. sapiens SSL Slorth 0.838511 View
ENSG00000101367 MAPRE1 ENSG00000165731 RET H. sapiens SSL Slorth 0.838503 View
ENSG00000101421 CHMP4B ENSG00000165731 RET H. sapiens SSL Slorth 0.838162 View
ENSG00000134909 ARHGAP32 ENSG00000165731 RET H. sapiens SSL Slorth 0.838014 View
ENSG00000102471 NDFIP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.837831 View
ENSG00000010292 NCAPD2 ENSG00000165731 RET H. sapiens SSL Slorth 0.837801 View
ENSG00000138443 ABI2 ENSG00000165731 RET H. sapiens SSL Slorth 0.837558 View
ENSG00000060971 ACAA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.83707 View
ENSG00000066777 ARFGEF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.837026 View
ENSG00000117528 ABCD3 ENSG00000165731 RET H. sapiens SSL Slorth 0.836444 View
ENSG00000118058 KMT2A ENSG00000165731 RET H. sapiens SSL Slorth 0.836363 View
ENSG00000126934 MAP2K2 ENSG00000165731 RET H. sapiens SSL Slorth 0.836333 View
ENSG00000070061 IKBKAP ENSG00000165731 RET H. sapiens SSL Slorth 0.835812 View
ENSG00000135766 EGLN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.835602 View
ENSG00000145555 MYO10 ENSG00000165731 RET H. sapiens SSL Slorth 0.835582 View
ENSG00000131165 CHMP1A ENSG00000165731 RET H. sapiens SSL Slorth 0.835463 View
ENSG00000149311 ATM ENSG00000165731 RET H. sapiens SSL Slorth 0.835237 View
ENSG00000092964 DPYSL2 ENSG00000165731 RET H. sapiens SSL Slorth 0.835153 View
ENSG00000132388 UBE2G1 ENSG00000165731 RET H. sapiens SSL Slorth 0.835082 View
ENSG00000130713 EXOSC2 ENSG00000165731 RET H. sapiens SSL Slorth 0.834846 View