KMT2A

ENSG00000118058 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0003680 AT DNA binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0018024 histone-lysine N-methyltransferase activity
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0045322 unmethylated CpG binding
GO:0070577 lysine-acetylated histone binding

Drugs

No drugs in record

Diseases

Disease Name
AML
ALL

Orthologs

Gene Organism
SET1 S. cerevisiae
trx D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113812 ACTR8 ENSG00000118058 KMT2A H. sapiens SSL BioGRID 1.0 View
ENSG00000141867 BRD4 ENSG00000118058 KMT2A H. sapiens SSL BioGRID 1.0 View
ENSG00000117139 KDM5B ENSG00000118058 KMT2A H. sapiens SSL BioGRID 1.0 View
ENSG00000012817 KDM5D ENSG00000118058 KMT2A H. sapiens SSL BioGRID 1.0 View
ENSG00000132510 KDM6B ENSG00000118058 KMT2A H. sapiens SSL BioGRID 1.0 View
ENSG00000118058 KMT2A ENSG00000133703 KRAS H. sapiens SSL BioGRID 1.0 View
ENSG00000118058 KMT2A ENSG00000042429 MED17 H. sapiens SSL BioGRID 1.0 View
ENSG00000118058 KMT2A ENSG00000164091 WDR82 H. sapiens SSL BioGRID 1.0 View
ENSG00000091831 ESR1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.983094 View
ENSG00000116478 HDAC1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.982684 View
ENSG00000012048 BRCA1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.978872 View
ENSG00000005339 CREBBP ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.97792 View
ENSG00000118058 KMT2A ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.97566 View
ENSG00000080824 HSP90AA1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.975645 View
ENSG00000113558 SKP1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.9743 View
ENSG00000118058 KMT2A ENSG00000150991 UBC H. sapiens SDL Slorth 0.973845 View
ENSG00000118058 KMT2A ENSG00000141510 TP53 H. sapiens SDL Slorth 0.97363 View
ENSG00000118058 KMT2A ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.972364 View
ENSG00000110107 PRPF19 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.971591 View
ENSG00000100393 EP300 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.971069 View
ENSG00000101266 CSNK2A1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.969827 View
ENSG00000118058 KMT2A ENSG00000173039 RELA H. sapiens SDL Slorth 0.964573 View
ENSG00000096384 HSP90AB1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.961803 View
ENSG00000100030 MAPK1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.956923 View
ENSG00000103275 UBE2I ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.953835 View
ENSG00000110395 CBL ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.950187 View
ENSG00000109670 FBXW7 ENSG00000118058 KMT2A H. sapiens SSL Slorth 0.949301 View
ENSG00000118058 KMT2A ENSG00000132646 PCNA H. sapiens SDL Slorth 0.946965 View
ENSG00000118058 KMT2A ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.941419 View
ENSG00000118058 KMT2A ENSG00000169083 AR H. sapiens SDL Slorth 0.939666 View
ENSG00000113575 PPP2CA ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.938838 View
ENSG00000118058 KMT2A ENSG00000197122 SRC H. sapiens SDL Slorth 0.938188 View
ENSG00000118058 KMT2A ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.936535 View
ENSG00000118058 KMT2A ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.936486 View
ENSG00000118058 KMT2A ENSG00000146648 EGFR H. sapiens SDL Slorth 0.935976 View
ENSG00000055130 CUL1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.935671 View
ENSG00000087191 PSMC5 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.934594 View
ENSG00000097007 ABL1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.933155 View
ENSG00000109320 NFKB1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.93186 View
ENSG00000118058 KMT2A ENSG00000139687 RB1 H. sapiens SDL Slorth 0.918598 View