RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000115170 ACVR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.820127 View
ENSG00000084234 APLP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.81983 View
ENSG00000106976 DNM1 ENSG00000165731 RET H. sapiens SSL Slorth 0.819634 View
ENSG00000142168 SOD1 ENSG00000165731 RET H. sapiens SSL Slorth 0.819269 View
ENSG00000047315 POLR2B ENSG00000165731 RET H. sapiens SSL Slorth 0.819061 View
ENSG00000126457 PRMT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.818617 View
ENSG00000034152 MAP2K3 ENSG00000165731 RET H. sapiens SSL Slorth 0.818382 View
ENSG00000142875 PRKACB ENSG00000165731 RET H. sapiens SSL Slorth 0.818072 View
ENSG00000092529 CAPN3 ENSG00000165731 RET H. sapiens SSL Slorth 0.817968 View
ENSG00000121067 SPOP ENSG00000165731 RET H. sapiens SSL Slorth 0.817882 View
ENSG00000087095 NLK ENSG00000165731 RET H. sapiens SSL Slorth 0.81781 View
ENSG00000158022 TRIM63 ENSG00000165731 RET H. sapiens SSL Slorth 0.817781 View
ENSG00000118515 SGK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.817719 View
ENSG00000115738 ID2 ENSG00000165731 RET H. sapiens SSL Slorth 0.817397 View
ENSG00000160948 VPS28 ENSG00000165731 RET H. sapiens SSL Slorth 0.817259 View
ENSG00000074181 NOTCH3 ENSG00000165731 RET H. sapiens SSL Slorth 0.817227 View
ENSG00000107263 RAPGEF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.816847 View
ENSG00000070018 LRP6 ENSG00000165731 RET H. sapiens SSL Slorth 0.816714 View
ENSG00000136279 DBNL ENSG00000165731 RET H. sapiens SSL Slorth 0.816367 View
ENSG00000165731 RET ENSG00000186716 BCR H. sapiens SSL Slorth 0.816325 View
ENSG00000063245 EPN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.816287 View
ENSG00000143799 PARP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.816191 View
ENSG00000141552 ANAPC11 ENSG00000165731 RET H. sapiens SSL Slorth 0.81581 View
ENSG00000106144 CASP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.81573 View
ENSG00000034713 GABARAPL2 ENSG00000165731 RET H. sapiens SSL Slorth 0.815425 View
ENSG00000105329 TGFB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.81518 View
ENSG00000165731 RET ENSG00000170027 YWHAG H. sapiens SSL Slorth 0.814901 View
ENSG00000099817 POLR2E ENSG00000165731 RET H. sapiens SSL Slorth 0.814473 View
ENSG00000014216 CAPN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.814006 View
ENSG00000012061 ERCC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.813888 View
ENSG00000104408 EIF3E ENSG00000165731 RET H. sapiens SSL Slorth 0.813618 View
ENSG00000163482 STK36 ENSG00000165731 RET H. sapiens SSL Slorth 0.813538 View
ENSG00000092969 TGFB2 ENSG00000165731 RET H. sapiens SSL Slorth 0.813513 View
ENSG00000143379 SETDB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.813381 View
ENSG00000115053 NCL ENSG00000165731 RET H. sapiens SSL Slorth 0.813245 View
ENSG00000105173 CCNE1 ENSG00000165731 RET H. sapiens SSL Slorth 0.813234 View
ENSG00000106636 YKT6 ENSG00000165731 RET H. sapiens SSL Slorth 0.813234 View
ENSG00000160867 FGFR4 ENSG00000165731 RET H. sapiens SSL Slorth 0.813175 View
ENSG00000101310 SEC23B ENSG00000165731 RET H. sapiens SSL Slorth 0.813009 View
ENSG00000119912 IDE ENSG00000165731 RET H. sapiens SSL Slorth 0.81297 View