RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000161638 ITGA5 ENSG00000165731 RET H. sapiens SSL Slorth 0.780462 View
ENSG00000165731 RET ENSG00000176105 YES1 H. sapiens SSL Slorth 0.780204 View
ENSG00000076944 STXBP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.780164 View
ENSG00000087470 DNM1L ENSG00000165731 RET H. sapiens SSL Slorth 0.780028 View
ENSG00000111641 NOP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.77998 View
ENSG00000152234 ATP5A1 ENSG00000165731 RET H. sapiens SSL Slorth 0.779733 View
ENSG00000112578 BYSL ENSG00000165731 RET H. sapiens SSL Slorth 0.779417 View
ENSG00000004478 FKBP4 ENSG00000165731 RET H. sapiens SSL Slorth 0.779353 View
ENSG00000122691 TWIST1 ENSG00000165731 RET H. sapiens SSL Slorth 0.779262 View
ENSG00000044115 CTNNA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.77793 View
ENSG00000137815 RTF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.777787 View
ENSG00000106105 GARS ENSG00000165731 RET H. sapiens SSL Slorth 0.77773 View
ENSG00000100554 ATP6V1D ENSG00000165731 RET H. sapiens SSL Slorth 0.777595 View
ENSG00000131462 TUBG1 ENSG00000165731 RET H. sapiens SSL Slorth 0.77722 View
ENSG00000111653 ING4 ENSG00000165731 RET H. sapiens SSL Slorth 0.7771 View
ENSG00000141198 TOM1L1 ENSG00000165731 RET H. sapiens SSL Slorth 0.776858 View
ENSG00000077150 NFKB2 ENSG00000165731 RET H. sapiens SSL Slorth 0.775986 View
ENSG00000133226 SRRM1 ENSG00000165731 RET H. sapiens SSL Slorth 0.775808 View
ENSG00000113722 CDX1 ENSG00000165731 RET H. sapiens SSL Slorth 0.775576 View
ENSG00000105402 NAPA ENSG00000165731 RET H. sapiens SSL Slorth 0.77528 View
ENSG00000165731 RET ENSG00000178999 AURKB H. sapiens SSL Slorth 0.775176 View
ENSG00000129084 PSMA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.774843 View
ENSG00000108587 GOSR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.774727 View
ENSG00000103365 GGA2 ENSG00000165731 RET H. sapiens SSL Slorth 0.774566 View
ENSG00000138795 LEF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.774374 View
ENSG00000106571 GLI3 ENSG00000165731 RET H. sapiens SSL Slorth 0.773388 View
ENSG00000129219 PLD2 ENSG00000165731 RET H. sapiens SSL Slorth 0.773149 View
ENSG00000110955 ATP5B ENSG00000165731 RET H. sapiens SSL Slorth 0.773025 View
ENSG00000101871 MID1 ENSG00000165731 RET H. sapiens SSL Slorth 0.772711 View
ENSG00000122367 LDB3 ENSG00000165731 RET H. sapiens SSL Slorth 0.772528 View
ENSG00000141556 TBCD ENSG00000165731 RET H. sapiens SSL Slorth 0.772493 View
ENSG00000165458 INPPL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.77237 View
ENSG00000069399 BCL3 ENSG00000165731 RET H. sapiens SSL Slorth 0.772301 View
ENSG00000063244 U2AF2 ENSG00000165731 RET H. sapiens SSL Slorth 0.772279 View
ENSG00000013275 PSMC4 ENSG00000165731 RET H. sapiens SSL Slorth 0.772012 View
ENSG00000137764 MAP2K5 ENSG00000165731 RET H. sapiens SSL Slorth 0.771977 View
ENSG00000165416 SUGT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.77183 View
ENSG00000121892 PDS5A ENSG00000165731 RET H. sapiens SSL Slorth 0.771693 View
ENSG00000163041 H3F3A ENSG00000165731 RET H. sapiens SSL Slorth 0.771416 View
ENSG00000115677 HDLBP ENSG00000165731 RET H. sapiens SSL Slorth 0.771284 View