RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000148943 LIN7C ENSG00000165731 RET H. sapiens SSL Slorth 0.770695 View
ENSG00000155438 NIFK ENSG00000165731 RET H. sapiens SSL Slorth 0.769767 View
ENSG00000134759 ELP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.769695 View
ENSG00000057663 ATG5 ENSG00000165731 RET H. sapiens SSL Slorth 0.769638 View
ENSG00000110719 TCIRG1 ENSG00000165731 RET H. sapiens SSL Slorth 0.769477 View
ENSG00000100347 SAMM50 ENSG00000165731 RET H. sapiens SSL Slorth 0.769396 View
ENSG00000165731 RET ENSG00000167461 RAB8A H. sapiens SSL Slorth 0.769052 View
ENSG00000165731 RET ENSG00000175390 EIF3F H. sapiens SSL Slorth 0.769008 View
ENSG00000122257 RBBP6 ENSG00000165731 RET H. sapiens SSL Slorth 0.768848 View
ENSG00000082781 ITGB5 ENSG00000165731 RET H. sapiens SSL Slorth 0.768644 View
ENSG00000125266 EFNB2 ENSG00000165731 RET H. sapiens SSL Slorth 0.768252 View
ENSG00000163914 RHO ENSG00000165731 RET H. sapiens SSL Slorth 0.768191 View
ENSG00000039537 C6 ENSG00000165731 RET H. sapiens SSL Slorth 0.768098 View
ENSG00000128578 STRIP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.768002 View
ENSG00000134597 RBMX2 ENSG00000165731 RET H. sapiens SSL Slorth 0.767643 View
ENSG00000165731 RET ENSG00000168090 COPS6 H. sapiens SSL Slorth 0.767304 View
ENSG00000109911 ELP4 ENSG00000165731 RET H. sapiens SSL Slorth 0.766895 View
ENSG00000165731 RET ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.766844 View
ENSG00000144848 ATG3 ENSG00000165731 RET H. sapiens SSL Slorth 0.766679 View
ENSG00000165731 RET ENSG00000167552 TUBA1A H. sapiens SSL Slorth 0.765885 View
ENSG00000164050 PLXNB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.765708 View
ENSG00000108344 PSMD3 ENSG00000165731 RET H. sapiens SSL Slorth 0.765237 View
ENSG00000146963 LUC7L2 ENSG00000165731 RET H. sapiens SSL Slorth 0.765219 View
ENSG00000112249 ASCC3 ENSG00000165731 RET H. sapiens SSL Slorth 0.765162 View
ENSG00000165731 RET ENSG00000196235 SUPT5H H. sapiens SSL Slorth 0.76459 View
ENSG00000165731 RET ENSG00000165806 CASP7 H. sapiens SSL Slorth 0.764234 View
ENSG00000109189 USP46 ENSG00000165731 RET H. sapiens SSL Slorth 0.764145 View
ENSG00000145216 FIP1L1 ENSG00000165731 RET H. sapiens SSL Slorth 0.764063 View
ENSG00000071127 WDR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.763804 View
ENSG00000162367 TAL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.76354 View
ENSG00000100697 DICER1 ENSG00000165731 RET H. sapiens SSL Slorth 0.763532 View
ENSG00000105647 PIK3R2 ENSG00000165731 RET H. sapiens SSL Slorth 0.763484 View
ENSG00000113141 IK ENSG00000165731 RET H. sapiens SSL Slorth 0.763389 View
ENSG00000105649 RAB3A ENSG00000165731 RET H. sapiens SSL Slorth 0.763195 View
ENSG00000077097 TOP2B ENSG00000165731 RET H. sapiens SSL Slorth 0.763063 View
ENSG00000159459 UBR1 ENSG00000165731 RET H. sapiens SSL Slorth 0.762681 View
ENSG00000131023 LATS1 ENSG00000165731 RET H. sapiens SSL Slorth 0.762628 View
ENSG00000132196 HSD17B7 ENSG00000165731 RET H. sapiens SSL Slorth 0.76233 View
ENSG00000151090 THRB ENSG00000165731 RET H. sapiens SSL Slorth 0.762276 View
ENSG00000101003 GINS1 ENSG00000165731 RET H. sapiens SSL Slorth 0.761789 View