RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000114166 KAT2B ENSG00000165731 RET H. sapiens SSL Slorth 0.812845 View
ENSG00000071794 HLTF ENSG00000165731 RET H. sapiens SSL Slorth 0.81279 View
ENSG00000004975 DVL2 ENSG00000165731 RET H. sapiens SSL Slorth 0.812452 View
ENSG00000080839 RBL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.812089 View
ENSG00000134352 IL6ST ENSG00000165731 RET H. sapiens SSL Slorth 0.812036 View
ENSG00000113312 TTC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.811987 View
ENSG00000118640 VAMP8 ENSG00000165731 RET H. sapiens SSL Slorth 0.811624 View
ENSG00000154001 PPP2R5E ENSG00000165731 RET H. sapiens SSL Slorth 0.811333 View
ENSG00000065000 AP3D1 ENSG00000165731 RET H. sapiens SSL Slorth 0.811155 View
ENSG00000104738 MCM4 ENSG00000165731 RET H. sapiens SSL Slorth 0.810978 View
ENSG00000122566 HNRNPA2B1 ENSG00000165731 RET H. sapiens SSL Slorth 0.810442 View
ENSG00000055118 KCNH2 ENSG00000165731 RET H. sapiens SSL Slorth 0.810401 View
ENSG00000114739 ACVR2B ENSG00000165731 RET H. sapiens SSL Slorth 0.810264 View
ENSG00000107201 DDX58 ENSG00000165731 RET H. sapiens SSL Slorth 0.809751 View
ENSG00000165731 RET ENSG00000171223 JUNB H. sapiens SSL Slorth 0.809637 View
ENSG00000108106 UBE2S ENSG00000165731 RET H. sapiens SSL Slorth 0.809201 View
ENSG00000110107 PRPF19 ENSG00000165731 RET H. sapiens SSL Slorth 0.809147 View
ENSG00000101557 USP14 ENSG00000165731 RET H. sapiens SSL Slorth 0.808907 View
ENSG00000111450 STX2 ENSG00000165731 RET H. sapiens SSL Slorth 0.808 View
ENSG00000163513 TGFBR2 ENSG00000165731 RET H. sapiens SSL Slorth 0.807973 View
ENSG00000129521 EGLN3 ENSG00000165731 RET H. sapiens SSL Slorth 0.807363 View
ENSG00000107341 UBE2R2 ENSG00000165731 RET H. sapiens SSL Slorth 0.807167 View
ENSG00000161800 RACGAP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.806907 View
ENSG00000144231 POLR2D ENSG00000165731 RET H. sapiens SSL Slorth 0.806728 View
ENSG00000143632 ACTA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.806619 View
ENSG00000133216 EPHB2 ENSG00000165731 RET H. sapiens SSL Slorth 0.80627 View
ENSG00000095139 ARCN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.806221 View
ENSG00000088808 PPP1R13B ENSG00000165731 RET H. sapiens SSL Slorth 0.806094 View
ENSG00000076555 ACACB ENSG00000165731 RET H. sapiens SSL Slorth 0.805902 View
ENSG00000107290 SETX ENSG00000165731 RET H. sapiens SSL Slorth 0.805847 View
ENSG00000165731 RET ENSG00000184634 MED12 H. sapiens SSL Slorth 0.805404 View
ENSG00000138430 OLA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.804867 View
ENSG00000082458 DLG3 ENSG00000165731 RET H. sapiens SSL Slorth 0.804335 View
ENSG00000095002 MSH2 ENSG00000165731 RET H. sapiens SSL Slorth 0.803969 View
ENSG00000165731 RET ENSG00000175197 DDIT3 H. sapiens SSL Slorth 0.803558 View
ENSG00000141985 SH3GL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.803513 View
ENSG00000165731 RET ENSG00000198554 WDHD1 H. sapiens SSL Slorth 0.802794 View
ENSG00000165731 RET ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.802555 View
ENSG00000117592 PRDX6 ENSG00000165731 RET H. sapiens SSL Slorth 0.801431 View
ENSG00000139567 ACVRL1 ENSG00000165731 RET H. sapiens SSL Slorth 0.801411 View