RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165731 RET ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.834768 View
ENSG00000076604 TRAF4 ENSG00000165731 RET H. sapiens SSL Slorth 0.834761 View
ENSG00000165731 RET ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.83475 View
ENSG00000105221 AKT2 ENSG00000165731 RET H. sapiens SSL Slorth 0.834747 View
ENSG00000154710 RABGEF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.834712 View
ENSG00000117751 PPP1R8 ENSG00000165731 RET H. sapiens SSL Slorth 0.83457 View
ENSG00000070756 PABPC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.834528 View
ENSG00000165731 RET ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.834261 View
ENSG00000124171 PARD6B ENSG00000165731 RET H. sapiens SSL Slorth 0.834244 View
ENSG00000070367 EXOC5 ENSG00000165731 RET H. sapiens SSL Slorth 0.834033 View
ENSG00000108946 PRKAR1A ENSG00000165731 RET H. sapiens SSL Slorth 0.833936 View
ENSG00000074800 ENO1 ENSG00000165731 RET H. sapiens SSL Slorth 0.83377 View
ENSG00000143093 STRIP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.833584 View
ENSG00000109805 NCAPG ENSG00000165731 RET H. sapiens SSL Slorth 0.833564 View
ENSG00000138668 HNRNPD ENSG00000165731 RET H. sapiens SSL Slorth 0.8335 View
ENSG00000139613 SMARCC2 ENSG00000165731 RET H. sapiens SSL Slorth 0.833411 View
ENSG00000145907 G3BP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.83317 View
ENSG00000164934 DCAF13 ENSG00000165731 RET H. sapiens SSL Slorth 0.833161 View
ENSG00000148606 POLR3A ENSG00000165731 RET H. sapiens SSL Slorth 0.833047 View
ENSG00000102755 FLT1 ENSG00000165731 RET H. sapiens SSL Slorth 0.832912 View
ENSG00000077254 USP33 ENSG00000165731 RET H. sapiens SSL Slorth 0.832842 View
ENSG00000126581 BECN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.832323 View
ENSG00000165731 RET ENSG00000273841 TAF9 H. sapiens SSL Slorth 0.832293 View
ENSG00000120705 ETF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.831753 View
ENSG00000116478 HDAC1 ENSG00000165731 RET H. sapiens SSL Slorth 0.831276 View
ENSG00000134001 EIF2S1 ENSG00000165731 RET H. sapiens SSL Slorth 0.83088 View
ENSG00000028528 SNX1 ENSG00000165731 RET H. sapiens SSL Slorth 0.830564 View
ENSG00000154767 XPC ENSG00000165731 RET H. sapiens SSL Slorth 0.830245 View
ENSG00000138758 SEPT11 ENSG00000165731 RET H. sapiens SSL Slorth 0.830069 View
ENSG00000122565 CBX3 ENSG00000165731 RET H. sapiens SSL Slorth 0.829817 View
ENSG00000104856 RELB ENSG00000165731 RET H. sapiens SSL Slorth 0.829794 View
ENSG00000165731 RET ENSG00000187555 USP7 H. sapiens SSL Slorth 0.829207 View
ENSG00000165731 RET ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.828719 View
ENSG00000116459 ATP5F1 ENSG00000165731 RET H. sapiens SSL Slorth 0.828516 View
ENSG00000151067 CACNA1C ENSG00000165731 RET H. sapiens SSL Slorth 0.828512 View
ENSG00000161203 AP2M1 ENSG00000165731 RET H. sapiens SSL Slorth 0.828236 View
ENSG00000124762 CDKN1A ENSG00000165731 RET H. sapiens SSL Slorth 0.828183 View
ENSG00000065054 SLC9A3R2 ENSG00000165731 RET H. sapiens SSL Slorth 0.828092 View
ENSG00000081479 LRP2 ENSG00000165731 RET H. sapiens SSL Slorth 0.828089 View
ENSG00000165731 RET ENSG00000169813 HNRNPF H. sapiens SSL Slorth 0.827926 View