DICER1 - RET

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DICER1	ENSG00000100697	sex cord-stromal tumour TGCT embryonal rhabdomyosarcoma pleuropulmonary blastoma pituitary blastoma Wilms tumour thyroid cancer other tumour types	No drugs in record	double-stranded RNA binding helicase activity endoribonuclease activity ribonuclease III activity deoxyribonuclease I activity protein binding ATP binding protein domain specific binding siRNA binding metal ion binding pre-miRNA binding	MPH1 (S. cerevisiae) dcr-1 (C. elegans) Dcr-1 (D. melanogaster)
RET	ENSG00000165731	medullary thyroid papillary thyroid pheochromocytoma NSCLC Spitzoid tumour	CABOZANTINIB LENVATINIB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor activity Ras guanyl-nucleotide exchange factor activity calcium ion binding protein binding ATP binding integrin binding	No GO terms in record