|
Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
|
KRAS
|
ENSG00000133703
|
pancreatic
colorectal
lung
thyroid
AML
other tumour types
|
No drugs in record
|
GTPase activity
protein binding
GTP binding
GMP binding
GDP binding
LRR domain binding
protein complex binding
|
RAS1 (S. cerevisiae)
RAS2 (S. cerevisiae)
let-60 (C. elegans)
Ras85D (D. melanogaster)
|
|
RET
|
ENSG00000165731
|
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour
|
CABOZANTINIB
LENVATINIB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
|
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor activity
Ras guanyl-nucleotide exchange factor activity
calcium ion binding
protein binding
ATP binding
integrin binding
|
No GO terms in record
|
