BTK - APC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BTK	ENSG00000010671	CLL mantle cell lymphoma WM	IBRUTINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding identical protein binding metal ion binding receptor binding	Btk29A (D. melanogaster)
APC	ENSG00000134982	colorectal pancreatic desmoid hepatoblastoma glioma other CNS	No drugs in record	protein binding beta-catenin binding microtubule binding protein kinase regulator activity protein kinase binding gamma-catenin binding microtubule plus-end binding cadherin binding	apr-1 (C. elegans) Apc2 (D. melanogaster) Apc (D. melanogaster)