CASP8 - HSP90AA1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
HSP90AA1	ENSG00000080824	NHL	No drugs in record	nucleotide binding glycoprotein binding UTP binding CTP binding mRNA binding protein tyrosine kinase activity protein binding ATP binding GTP binding ATPase activity sulfonylurea receptor binding protein phosphatase binding MHC class II protein complex binding nitric-oxide synthase regulator activity TPR domain binding dATP binding identical protein binding protein homodimerization activity histone deacetylase binding ion channel binding tau protein binding GTPase binding Rho GDP-dissociation inhibitor binding unfolded protein binding protein tyrosine kinase binding	HSC82 (S. cerevisiae) HSP82 (S. cerevisiae) daf-21 (C. elegans) Hsp83 (D. melanogaster)