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CFTR - CASP8
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
CFTR
ENSG00000001626
No diseases in record
CROFELEMER
IVACAFTOR
LUMACAFTOR
chloride channel activity
intracellular ATPase-gated chloride channel activity
protein binding
ATP binding
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
chloride channel regulator activity
chloride channel inhibitor activity
enzyme binding
PDZ domain binding
ATPase-coupled anion transmembrane transporter activity
BPT1 (S. cerevisiae)
CASP8
ENSG00000064012
hepatocellular
oral squamous cell
breast
No drugs in record
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)