CASP8 - CDK9

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
CDK9	ENSG00000136807	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding transcription coactivator binding DNA binding chromatin binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity kinase activity 7SK snRNA binding transcription factor binding cyclin binding transcription regulatory region DNA binding cyclin-dependent protein kinase activity	CTK1 (S. cerevisiae) cdk-9 (C. elegans) Cdk9 (D. melanogaster)