H. sapiens

SDL interaction


Gene Name Gene ID Diseases Drugs GO terms Orthologs
CASP8 ENSG00000064012 hepatocellular
oral squamous cell

No drugs in record

cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)
KDM5A ENSG00000073614 AML

No drugs in record

DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
zinc ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
chromatin DNA binding
histone demethylase activity
JHD2 (S. cerevisiae)
rbr-2 (C. elegans)