PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000128245 YWHAH ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.96348 View
ENSG00000143799 PARP1 ENSG00000196235 SUPT5H H. sapiens SSL Slorth 0.96342 View
ENSG00000072518 MARK2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.963387 View
ENSG00000143799 PARP1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.963267 View
ENSG00000117707 PROX1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.963264 View
ENSG00000062822 POLD1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.963247 View
ENSG00000143799 PARP1 ENSG00000170027 YWHAG H. sapiens SSL Slorth 0.963223 View
ENSG00000143799 PARP1 ENSG00000196419 XRCC6 H. sapiens SDL Slorth 0.963116 View
ENSG00000115507 OTX1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.963086 View
ENSG00000143799 PARP1 ENSG00000197879 MYO1C H. sapiens SDL Slorth 0.962999 View
ENSG00000112592 TBP ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.962993 View
ENSG00000078140 UBE2K ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.962937 View
ENSG00000143799 PARP1 ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.962892 View
ENSG00000029639 TFB1M ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.962869 View
ENSG00000143799 PARP1 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.962833 View
ENSG00000134138 MEIS2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.962782 View
ENSG00000143799 PARP1 ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.962758 View
ENSG00000089159 PXN ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.962707 View
ENSG00000143799 PARP1 ENSG00000160224 AIRE H. sapiens SDL Slorth 0.962692 View
ENSG00000102145 GATA1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.96268 View
ENSG00000143799 PARP1 ENSG00000155846 PPARGC1B H. sapiens SDL Slorth 0.962672 View
ENSG00000100030 MAPK1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.962651 View
ENSG00000143799 PARP1 ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.962452 View
ENSG00000143799 PARP1 ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.962424 View
ENSG00000080824 HSP90AA1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.962393 View
ENSG00000105810 CDK6 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.962291 View
ENSG00000143294 PRCC ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.962289 View
ENSG00000143799 PARP1 ENSG00000186575 NF2 H. sapiens SDL Slorth 0.962275 View
ENSG00000136997 MYC ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.962232 View
ENSG00000061938 TNK2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.962214 View
ENSG00000077097 TOP2B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.961951 View
ENSG00000143799 PARP1 ENSG00000144668 ITGA9 H. sapiens SDL Slorth 0.961949 View
ENSG00000143799 PARP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.961887 View
ENSG00000143799 PARP1 ENSG00000170315 UBB H. sapiens SDL Slorth 0.961821 View
ENSG00000143799 PARP1 ENSG00000162302 RPS6KA4 H. sapiens SDL Slorth 0.96182 View
ENSG00000143799 PARP1 ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.961806 View
ENSG00000101966 XIAP ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.961659 View
ENSG00000143799 PARP1 ENSG00000161547 SRSF2 H. sapiens SSL Slorth 0.961547 View
ENSG00000113575 PPP2CA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.961514 View
ENSG00000136450 SRSF1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.961448 View