PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.96141 View
ENSG00000143799 PARP1 ENSG00000165416 SUGT1 H. sapiens SSL Slorth 0.961394 View
ENSG00000063438 AHRR ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.961356 View
ENSG00000106462 EZH2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.961315 View
ENSG00000143799 PARP1 ENSG00000147274 RBMX H. sapiens SSL Slorth 0.961269 View
ENSG00000143799 PARP1 ENSG00000150907 FOXO1 H. sapiens SSL Slorth 0.961216 View
ENSG00000143799 PARP1 ENSG00000146457 WTAP H. sapiens SDL Slorth 0.961199 View
ENSG00000106689 LHX2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.961155 View
ENSG00000143799 PARP1 ENSG00000186575 NF2 H. sapiens SSL Slorth 0.961144 View
ENSG00000113575 PPP2CA ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.961109 View
ENSG00000130751 NPAS1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.9611 View
ENSG00000143799 PARP1 ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.961073 View
ENSG00000141646 SMAD4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.961039 View
ENSG00000143799 PARP1 ENSG00000184634 MED12 H. sapiens SSL Slorth 0.961023 View
ENSG00000143799 PARP1 ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.960982 View
ENSG00000143799 PARP1 ENSG00000198742 SMURF1 H. sapiens SDL Slorth 0.96097 View
ENSG00000143799 PARP1 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.960926 View
ENSG00000072062 PRKACA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.960916 View
ENSG00000143799 PARP1 ENSG00000157601 MX1 H. sapiens SDL Slorth 0.960849 View
ENSG00000143799 PARP1 ENSG00000149554 CHEK1 H. sapiens SDL Slorth 0.960722 View
ENSG00000143799 PARP1 ENSG00000163743 RCHY1 H. sapiens SSL Slorth 0.960695 View
ENSG00000143799 PARP1 ENSG00000187109 NAP1L1 H. sapiens SSL Slorth 0.960604 View
ENSG00000136944 LMX1B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.96054 View
ENSG00000114315 HES1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.960531 View
ENSG00000143799 PARP1 ENSG00000167986 DDB1 H. sapiens SDL Slorth 0.960524 View
ENSG00000075624 ACTB ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.960449 View
ENSG00000143799 PARP1 ENSG00000182511 FES H. sapiens SDL Slorth 0.960448 View
ENSG00000122592 HOXA7 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.96039 View
ENSG00000101665 SMAD7 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.960345 View
ENSG00000143799 PARP1 ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.960246 View
ENSG00000097007 ABL1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.960195 View
ENSG00000143799 PARP1 ENSG00000147614 ATP6V0D2 H. sapiens SDL Slorth 0.960191 View
ENSG00000016082 ISL1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.960172 View
ENSG00000143799 PARP1 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.959913 View
ENSG00000143799 PARP1 ENSG00000149480 MTA2 H. sapiens SSL Slorth 0.959888 View
ENSG00000143799 PARP1 ENSG00000162909 CAPN2 H. sapiens SDL Slorth 0.959872 View
ENSG00000070159 PTPN3 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.95987 View
ENSG00000134363 FST ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.959841 View
ENSG00000143799 PARP1 ENSG00000157933 SKI H. sapiens SSL Slorth 0.959817 View
ENSG00000143799 PARP1 ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.959684 View