PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000139154 AEBP2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.954487 View
ENSG00000112062 MAPK14 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.954449 View
ENSG00000143799 PARP1 ENSG00000172845 SP3 H. sapiens SDL Slorth 0.954383 View
ENSG00000143799 PARP1 ENSG00000146457 WTAP H. sapiens SSL Slorth 0.954381 View
ENSG00000093009 CDC45 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.954314 View
ENSG00000141480 ARRB2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.95429 View
ENSG00000143799 PARP1 ENSG00000144852 NR1I2 H. sapiens SDL Slorth 0.954175 View
ENSG00000143799 PARP1 ENSG00000156475 PPP2R2B H. sapiens SDL Slorth 0.954165 View
ENSG00000114742 WDR48 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.954162 View
ENSG00000143799 PARP1 ENSG00000183072 NKX2-5 H. sapiens SDL Slorth 0.95407 View
ENSG00000143799 PARP1 ENSG00000153147 SMARCA5 H. sapiens SDL Slorth 0.95404 View
ENSG00000101213 PTK6 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.953773 View
ENSG00000143799 PARP1 ENSG00000198887 SMC5 H. sapiens SDL Slorth 0.953765 View
ENSG00000116016 EPAS1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.953764 View
ENSG00000102882 MAPK3 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.953755 View
ENSG00000143799 PARP1 ENSG00000164104 HMGB2 H. sapiens SDL Slorth 0.953556 View
ENSG00000143799 PARP1 ENSG00000175792 RUVBL1 H. sapiens SDL Slorth 0.953339 View
ENSG00000131747 TOP2A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.953319 View
ENSG00000143799 PARP1 ENSG00000197930 ERO1A H. sapiens SDL Slorth 0.953304 View
ENSG00000143799 PARP1 ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.953182 View
ENSG00000143799 PARP1 ENSG00000198431 TXNRD1 H. sapiens SSL Slorth 0.9531 View
ENSG00000143799 PARP1 ENSG00000163161 ERCC3 H. sapiens SDL Slorth 0.952705 View
ENSG00000143799 PARP1 ENSG00000167996 FTH1 H. sapiens SDL Slorth 0.952695 View
ENSG00000143799 PARP1 ENSG00000164362 TERT H. sapiens SDL Slorth 0.952688 View
ENSG00000143799 PARP1 ENSG00000180353 HCLS1 H. sapiens SDL Slorth 0.952521 View
ENSG00000101412 E2F1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.952512 View
ENSG00000143799 PARP1 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.952467 View
ENSG00000143799 PARP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.952435 View
ENSG00000134308 YWHAQ ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.952399 View
ENSG00000143799 PARP1 ENSG00000254772 EEF1G H. sapiens SSL Slorth 0.952367 View
ENSG00000124813 RUNX2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.952339 View
ENSG00000132170 PPARG ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.952272 View
ENSG00000143799 PARP1 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.952247 View
ENSG00000079387 SENP1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.952133 View
ENSG00000140992 PDPK1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.952122 View
ENSG00000132849 PATJ ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.952001 View
ENSG00000143799 PARP1 ENSG00000196611 MMP1 H. sapiens SDL Slorth 0.951944 View
ENSG00000143799 PARP1 ENSG00000153487 ING1 H. sapiens SSL Slorth 0.951915 View
ENSG00000143799 PARP1 ENSG00000157954 WIPI2 H. sapiens SDL Slorth 0.951846 View
ENSG00000143799 PARP1 ENSG00000196712 NF1 H. sapiens SDL Slorth 0.951846 View