TOP1MT

ENSG00000184428 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003917 DNA topoisomerase type I activity

Drugs

Drug name Description
IRINOTECAN DNA topoisomerase I inhibitor
TOPOTECAN DNA topoisomerase I, mitochondrial inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP1 S. cerevisiae
top-1 C. elegans
Top1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000139687 RB1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.988735 View
ENSG00000136997 MYC ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.988347 View
ENSG00000012048 BRCA1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.98712 View
ENSG00000123374 CDK2 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.984964 View
ENSG00000177606 JUN ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.984747 View
ENSG00000169375 SIN3A ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.984721 View
ENSG00000103275 UBE2I ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.9846 View
ENSG00000149311 ATM ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.983927 View
ENSG00000005339 CREBBP ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.982127 View
ENSG00000132646 PCNA ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.981249 View
ENSG00000132383 RPA1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.980539 View
ENSG00000140464 PML ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.980165 View
ENSG00000113558 SKP1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.979594 View
ENSG00000184428 TOP1MT ENSG00000197122 SRC H. sapiens SDL Slorth 0.978864 View
ENSG00000170315 UBB ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.978701 View
ENSG00000077097 TOP2B ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.977648 View
ENSG00000113575 PPP2CA ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.977488 View
ENSG00000131747 TOP2A ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.977027 View
ENSG00000109670 FBXW7 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.976648 View
ENSG00000165280 VCP ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.976022 View
ENSG00000124762 CDKN1A ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.974353 View
ENSG00000133703 KRAS ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.972904 View
ENSG00000082701 GSK3B ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.972581 View
ENSG00000084774 CAD ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.972402 View
ENSG00000055130 CUL1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.9706 View
ENSG00000174231 PRPF8 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.969972 View
ENSG00000122406 RPL5 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.969285 View
ENSG00000149273 RPS3 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.968595 View
ENSG00000112062 MAPK14 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.967576 View
ENSG00000142534 RPS11 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.966863 View
ENSG00000166913 YWHAB ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.966776 View
ENSG00000141027 NCOR1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.966074 View
ENSG00000165392 WRN ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.965113 View
ENSG00000163960 UBXN7 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.965085 View
ENSG00000141646 SMAD4 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.964982 View
ENSG00000112592 TBP ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.964425 View
ENSG00000099956 SMARCB1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.963692 View
ENSG00000184428 TOP1MT ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.963455 View
ENSG00000100030 MAPK1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.963201 View
ENSG00000183207 RUVBL2 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.96153 View