TOP1MT

ENSG00000184428 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003917 DNA topoisomerase type I activity

Drugs

Drug name Description
IRINOTECAN DNA topoisomerase I inhibitor
TOPOTECAN DNA topoisomerase I, mitochondrial inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP1 S. cerevisiae
top-1 C. elegans
Top1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.785826 View
ENSG00000145604 SKP2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.781873 View
ENSG00000104365 IKBKB ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.781627 View
ENSG00000169750 RAC3 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.780753 View
ENSG00000123374 CDK2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.779601 View
ENSG00000170315 UBB ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.775173 View
ENSG00000138069 RAB1A ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.772098 View
ENSG00000116288 PARK7 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.770358 View
ENSG00000103275 UBE2I ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.768496 View
ENSG00000136937 NCBP1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.767095 View
ENSG00000100644 HIF1A ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.76644 View
ENSG00000164305 CASP3 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.765894 View
ENSG00000169139 UBE2V2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.762182 View
ENSG00000149311 ATM ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.761423 View
ENSG00000177885 GRB2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.76029 View
ENSG00000146648 EGFR ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.760202 View
ENSG00000175387 SMAD2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.757618 View
ENSG00000132646 PCNA ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.754433 View
ENSG00000114166 KAT2B ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.753816 View
ENSG00000166501 PRKCB ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.753188 View
ENSG00000073111 MCM2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.752208 View
ENSG00000141027 NCOR1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.751934 View
ENSG00000183207 RUVBL2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.751238 View