TOP1MT

ENSG00000184428 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003917 DNA topoisomerase type I activity

Drugs

Drug name Description
IRINOTECAN DNA topoisomerase I inhibitor
TOPOTECAN DNA topoisomerase I, mitochondrial inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP1 S. cerevisiae
top-1 C. elegans
Top1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000173039 RELA ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.921297 View
ENSG00000112306 RPS12 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.920934 View
ENSG00000102882 MAPK3 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.920807 View
ENSG00000163930 BAP1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.920589 View
ENSG00000137818 RPLP1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.919995 View
ENSG00000097007 ABL1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.919675 View
ENSG00000143799 PARP1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.919202 View
ENSG00000175054 ATR ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.915772 View
ENSG00000100030 MAPK1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.91544 View
ENSG00000096384 HSP90AB1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.915181 View
ENSG00000004700 RECQL ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.914483 View
ENSG00000140464 PML ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.913746 View
ENSG00000068024 HDAC4 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.912547 View
ENSG00000166167 BTRC ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.911901 View
ENSG00000111276 CDKN1B ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.911327 View
ENSG00000184428 TOP1MT ENSG00000185591 SP1 H. sapiens SDL Slorth 0.9107 View
ENSG00000165025 SYK ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.909205 View
ENSG00000100387 RBX1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.908439 View
ENSG00000110395 CBL ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.907965 View
ENSG00000121022 COPS5 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.906434 View
ENSG00000071082 RPL31 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.906372 View
ENSG00000080824 HSP90AA1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.90562 View
ENSG00000168036 CTNNB1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.903093 View
ENSG00000149554 CHEK1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.902774 View
ENSG00000101412 E2F1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.90235 View
ENSG00000130939 UBE4B ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.902012 View
ENSG00000089157 RPLP0 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.901405 View
ENSG00000164305 CASP3 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.901095 View
ENSG00000117133 RPF1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.89669 View
ENSG00000101412 E2F1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.896266 View
ENSG00000133316 WDR74 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.894224 View
ENSG00000082701 GSK3B ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.890213 View
ENSG00000012048 BRCA1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.885522 View
ENSG00000173039 RELA ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.885242 View
ENSG00000134086 VHL ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.884637 View
ENSG00000101868 POLA1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.883671 View
ENSG00000167552 TUBA1A ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.875376 View
ENSG00000112062 MAPK14 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.871923 View
ENSG00000128908 INO80 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.871101 View
ENSG00000171791 BCL2 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.870877 View