TOP1MT

ENSG00000184428 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003917 DNA topoisomerase type I activity

Drugs

Drug name Description
IRINOTECAN DNA topoisomerase I inhibitor
TOPOTECAN DNA topoisomerase I, mitochondrial inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP1 S. cerevisiae
top-1 C. elegans
Top1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000168028 RPSA ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.940591 View
ENSG00000116478 HDAC1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.940404 View
ENSG00000164924 YWHAZ ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.939295 View
ENSG00000167658 EEF2 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.939262 View
ENSG00000136997 MYC ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.939203 View
ENSG00000156482 RPL30 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.938492 View
ENSG00000132155 RAF1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.938216 View
ENSG00000101966 XIAP ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.937586 View
ENSG00000159377 PSMB4 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.937381 View
ENSG00000169083 AR ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.937192 View
ENSG00000172809 RPL38 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.936935 View
ENSG00000116251 RPL22 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.936442 View
ENSG00000010810 FYN ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.935421 View
ENSG00000143106 PSMA5 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.934997 View
ENSG00000147133 TAF1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.934871 View
ENSG00000129084 PSMA1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.934614 View
ENSG00000162385 MAGOH ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.933697 View
ENSG00000008018 PSMB1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.933473 View
ENSG00000047315 POLR2B ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.933458 View
ENSG00000105372 RPS19 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.933199 View
ENSG00000175387 SMAD2 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.933194 View
ENSG00000145592 RPL37 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.932281 View
ENSG00000097046 CDC7 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.932078 View
ENSG00000167986 DDB1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.931977 View
ENSG00000108298 RPL19 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.930866 View
ENSG00000177885 GRB2 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.929304 View
ENSG00000069869 NEDD4 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.929117 View
ENSG00000099341 PSMD8 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.928364 View
ENSG00000184428 TOP1MT ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.927997 View
ENSG00000184428 TOP1MT ENSG00000198900 TOP1 H. sapiens SDL Slorth 0.926042 View
ENSG00000070831 CDC42 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.925728 View
ENSG00000104365 IKBKB ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.925267 View
ENSG00000124614 RPS10 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.924765 View
ENSG00000171858 RPS21 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.924361 View
ENSG00000101146 RAE1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.924331 View
ENSG00000100138 SNU13 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.924084 View
ENSG00000091831 ESR1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.92359 View
ENSG00000177600 RPLP2 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.923409 View
ENSG00000105640 RPL18A ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.92332 View
ENSG00000100029 PES1 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.922357 View