Go term | Description |
---|---|
GO:0003677 | DNA binding |
GO:0003917 | DNA topoisomerase type I activity |
Drug name | Description |
---|---|
IRINOTECAN | DNA topoisomerase I inhibitor |
TOPOTECAN | DNA topoisomerase I, mitochondrial inhibitor |
No diseases in record
Gene | Organism | |
---|---|---|
TOP1 | S. cerevisiae | |
top-1 | C. elegans | |
Top1 | D. melanogaster |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000177606 | JUN | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.870369 | View |
ENSG00000164924 | YWHAZ | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.867521 | View |
ENSG00000169083 | AR | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.863817 | View |
ENSG00000142208 | AKT1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.863335 | View |
ENSG00000168610 | STAT3 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.859777 | View |
ENSG00000113575 | PPP2CA | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.858032 | View |
ENSG00000170312 | CDK1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.857493 | View |
ENSG00000114767 | RRP9 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.856111 | View |
ENSG00000049759 | NEDD4L | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.855453 | View |
ENSG00000141646 | SMAD4 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.854656 | View |
ENSG00000124762 | CDKN1A | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.854537 | View |
ENSG00000010810 | FYN | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.854307 | View |
ENSG00000169375 | SIN3A | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.848787 | View |
ENSG00000110713 | NUP98 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.848243 | View |
ENSG00000096717 | SIRT1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.842149 | View |
ENSG00000135624 | CCT7 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.841606 | View |
ENSG00000070010 | UFD1L | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.835825 | View |
ENSG00000109971 | HSPA8 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.835686 | View |
ENSG00000175104 | TRAF6 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.83297 | View |
ENSG00000139687 | RB1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.827665 | View |
ENSG00000115816 | CEBPZ | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.827074 | View |
ENSG00000177889 | UBE2N | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.826822 | View |
ENSG00000123124 | WWP1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.825208 | View |
ENSG00000166949 | SMAD3 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.819195 | View |
ENSG00000109320 | NFKB1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.819027 | View |
ENSG00000126261 | UBA2 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.818344 | View |
ENSG00000116030 | SUMO1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.813527 | View |
ENSG00000101266 | CSNK2A1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.812591 | View |
ENSG00000005339 | CREBBP | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.811165 | View |
ENSG00000136807 | CDK9 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.810995 | View |
ENSG00000160803 | UBQLN4 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.810614 | View |
ENSG00000112592 | TBP | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.804161 | View |
ENSG00000168283 | BMI1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.801212 | View |
ENSG00000108443 | RPS6KB1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.800049 | View |
ENSG00000154473 | BUB3 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.796728 | View |
ENSG00000062822 | POLD1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.792839 | View |
ENSG00000149554 | CHEK1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.790345 | View |
ENSG00000006451 | RALA | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.786453 | View |
ENSG00000132155 | RAF1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.785875 | View |
ENSG00000149136 | SSRP1 | ENSG00000184428 | TOP1MT | H. sapiens | SSL | Slorth | 0.785841 | View |