APEX1

ENSG00000100823 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003691 double-stranded telomeric DNA binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity
GO:0004519 endonuclease activity
GO:0004520 endodeoxyribonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004528 phosphodiesterase I activity
GO:0004844 uracil DNA N-glycosylase activity
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity
GO:0008309 double-stranded DNA exodeoxyribonuclease activity
GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016491 oxidoreductase activity
GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base
GO:0031490 chromatin DNA binding
GO:0032403 protein complex binding
GO:0046872 metal ion binding
GO:0051059 NF-kappaB binding

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
APN2 S. cerevisiae
exo-3 C. elegans
Rrp1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000100823 APEX1 ENSG00000149311 ATM H. sapiens SSL BioGRID 1.0 View
ENSG00000100823 APEX1 ENSG00000139618 BRCA2 H. sapiens SSL BioGRID 1.0 View
ENSG00000100823 APEX1 ENSG00000143799 PARP1 H. sapiens SSL BioGRID 1.0 View
ENSG00000100823 APEX1 ENSG00000253729 PRKDC H. sapiens SSL BioGRID 1.0 View
ENSG00000005339 CREBBP ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.989406 View
ENSG00000091831 ESR1 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.989261 View
ENSG00000012048 BRCA1 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.987873 View
ENSG00000100393 EP300 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.982973 View
ENSG00000100823 APEX1 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.982261 View
ENSG00000100823 APEX1 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.98136 View
ENSG00000100823 APEX1 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.980617 View
ENSG00000100823 APEX1 ENSG00000136997 MYC H. sapiens SDL Slorth 0.979788 View
ENSG00000100823 APEX1 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.979121 View
ENSG00000100823 APEX1 ENSG00000170315 UBB H. sapiens SDL Slorth 0.978489 View
ENSG00000100823 APEX1 ENSG00000169083 AR H. sapiens SDL Slorth 0.978337 View
ENSG00000100823 APEX1 ENSG00000197122 SRC H. sapiens SDL Slorth 0.975316 View
ENSG00000100823 APEX1 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.975256 View
ENSG00000100823 APEX1 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.974904 View
ENSG00000100823 APEX1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.974647 View
ENSG00000080824 HSP90AA1 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.974205 View
ENSG00000100823 APEX1 ENSG00000177606 JUN H. sapiens SDL Slorth 0.971085 View
ENSG00000012048 BRCA1 ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.971003 View
ENSG00000005339 CREBBP ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.9709 View
ENSG00000087191 PSMC5 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.970749 View
ENSG00000100823 APEX1 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.969159 View
ENSG00000100823 APEX1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.968837 View
ENSG00000100823 APEX1 ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.966982 View
ENSG00000100823 APEX1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.966396 View
ENSG00000100030 MAPK1 ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.966332 View
ENSG00000100644 HIF1A ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.965104 View
ENSG00000072401 UBE2D1 ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.963682 View
ENSG00000080815 PSEN1 ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.957983 View
ENSG00000082701 GSK3B ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.95508 View
ENSG00000100823 APEX1 ENSG00000136273 HUS1 H. sapiens SDL Slorth 0.954109 View
ENSG00000041357 PSMA4 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.952347 View
ENSG00000091831 ESR1 ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.951181 View
ENSG00000010810 FYN ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.949865 View
ENSG00000097007 ABL1 ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.949528 View
ENSG00000097046 CDC7 ENSG00000100823 APEX1 H. sapiens SSL Slorth 0.947652 View
ENSG00000100201 DDX17 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.946924 View