SMAD2 - RYR1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SMAD2 ENSG00000175387 colorectal carcinoma
hepatocellular carcinoma

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
transcription factor binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
ubiquitin protein ligase binding
activating transcription factor binding
type I transforming growth factor beta receptor binding
enhancer binding
protein homodimerization activity
SMAD binding
metal ion binding
protein heterodimerization activity
co-SMAD binding
I-SMAD binding
R-SMAD binding
DNA binding
sma-3 (C. elegans)
sma-2 (C. elegans)
RYR1 ENSG00000196218

No diseases in record

DANTROLENE
protease binding
ryanodine-sensitive calcium-release channel activity
voltage-gated calcium channel activity
calcium channel activity
calcium ion binding
protein binding
calmodulin binding
calcium-release channel activity
calcium-induced calcium release activity
RyR (D. melanogaster)