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Slorth
FBXW7 - NOTCH1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
FBXW7
ENSG00000109670
colorectal
endometrial
T-ALL
No drugs in record
ubiquitin-protein transferase activity
protein binding
cyclin binding
protein binding, bridging
ubiquitin protein ligase binding
identical protein binding
phosphothreonine residue binding
ubiquitin-protein transferase activator activity
MET30 (S. cerevisiae)
sel-10 (C. elegans)
ago (D. melanogaster)
NOTCH1
ENSG00000148400
T-ALL
breast
bladder
skin SCC
lung SCC
head and neck SCC
No drugs in record
core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
enzyme inhibitor activity
receptor activity
Notch binding
calcium ion binding
protein binding
enzyme binding
chromatin DNA binding
sequence-specific DNA binding
protein heterodimerization activity
N (D. melanogaster)