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Slorth
SIRT1 - BLM
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
SIRT1
ENSG00000096717
No diseases in record
No drugs in record
core promoter sequence-specific DNA binding
p53 binding
transcription corepressor activity
histone deacetylase activity
protein binding
protein C-terminus binding
transcription factor binding
NAD-dependent histone deacetylase activity
deacetylase activity
enzyme binding
protein deacetylase activity
NAD-dependent protein deacetylase activity
nuclear hormone receptor binding
histone binding
identical protein binding
HLH domain binding
bHLH transcription factor binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
mitogen-activated protein kinase binding
NAD+ binding
keratin filament binding
NAD+ ADP-ribosyltransferase activity
HST1 (S. cerevisiae)
SIR2 (S. cerevisiae)
sir-2.1 (C. elegans)
BLM
ENSG00000197299
leukaemia
lymphoma
skin squamous cell
other tumour types
No drugs in record
bubble DNA binding
p53 binding
single-stranded DNA binding
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
ATP-dependent helicase activity
four-way junction helicase activity
ATPase activity
annealing helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
DNA helicase activity
DNA-dependent ATPase activity
Y-form DNA binding
SGS1 (S. cerevisiae)
him-6 (C. elegans)
Blm (D. melanogaster)