SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000169016 E2F6 H. sapiens SSL Slorth 0.75329 View
ENSG00000096717 SIRT1 ENSG00000139197 PEX5 H. sapiens SSL Slorth 0.752962 View
ENSG00000096717 SIRT1 ENSG00000127463 EMC1 H. sapiens SSL Slorth 0.752939 View
ENSG00000096717 SIRT1 ENSG00000103342 GSPT1 H. sapiens SSL Slorth 0.752765 View
ENSG00000096717 SIRT1 ENSG00000116489 CAPZA1 H. sapiens SSL Slorth 0.752623 View
ENSG00000096717 SIRT1 ENSG00000160214 RRP1 H. sapiens SSL Slorth 0.752478 View
ENSG00000033627 ATP6V0A1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.752247 View
ENSG00000096717 SIRT1 ENSG00000163399 ATP1A1 H. sapiens SSL Slorth 0.752137 View
ENSG00000096717 SIRT1 ENSG00000196961 AP2A1 H. sapiens SSL Slorth 0.751971 View
ENSG00000096717 SIRT1 ENSG00000160271 RALGDS H. sapiens SSL Slorth 0.751287 View
ENSG00000096717 SIRT1 ENSG00000173145 NOC3L H. sapiens SSL Slorth 0.751133 View
ENSG00000096717 SIRT1 ENSG00000117528 ABCD3 H. sapiens SSL Slorth 0.750918 View
ENSG00000096717 SIRT1 ENSG00000255112 CHMP1B H. sapiens SSL Slorth 0.750773 View
ENSG00000096717 SIRT1 ENSG00000142864 SERBP1 H. sapiens SSL Slorth 0.750749 View
ENSG00000096717 SIRT1 ENSG00000117758 STX12 H. sapiens SSL Slorth 0.750722 View
ENSG00000096717 SIRT1 ENSG00000125868 DSTN H. sapiens SSL Slorth 0.750505 View
ENSG00000042088 TDP1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.750497 View
ENSG00000096717 SIRT1 ENSG00000183020 AP2A2 H. sapiens SSL Slorth 0.75045 View
ENSG00000096717 SIRT1 ENSG00000174437 ATP2A2 H. sapiens SSL Slorth 0.75034 View
ENSG00000096717 SIRT1 ENSG00000108179 PPIF H. sapiens SSL Slorth 0.750226 View
ENSG00000096717 SIRT1 ENSG00000155111 CDK19 H. sapiens SSL Slorth 0.750065 View