SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000188229 TUBB4B H. sapiens SSL Slorth 0.79256 View
ENSG00000096717 SIRT1 ENSG00000178295 GEN1 H. sapiens SSL Slorth 0.792328 View
ENSG00000096717 SIRT1 ENSG00000157168 NRG1 H. sapiens SSL Slorth 0.79228 View
ENSG00000096717 SIRT1 ENSG00000110777 POU2AF1 H. sapiens SSL Slorth 0.79195 View
ENSG00000065000 AP3D1 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.791941 View
ENSG00000096717 SIRT1 ENSG00000157227 MMP14 H. sapiens SSL Slorth 0.791905 View
ENSG00000096717 SIRT1 ENSG00000103723 AP3B2 H. sapiens SSL Slorth 0.79175 View
ENSG00000096717 SIRT1 ENSG00000182774 RPS17 H. sapiens SSL Slorth 0.791713 View
ENSG00000096717 SIRT1 ENSG00000170881 RNF139 H. sapiens SSL Slorth 0.791506 View
ENSG00000096717 SIRT1 ENSG00000115760 BIRC6 H. sapiens SSL Slorth 0.791448 View
ENSG00000096717 SIRT1 ENSG00000175324 LSM1 H. sapiens SSL Slorth 0.791409 View
ENSG00000096717 SIRT1 ENSG00000127314 RAP1B H. sapiens SSL Slorth 0.791331 View
ENSG00000096717 SIRT1 ENSG00000169696 ASPSCR1 H. sapiens SSL Slorth 0.79123 View
ENSG00000096717 SIRT1 ENSG00000170860 LSM3 H. sapiens SSL Slorth 0.791223 View
ENSG00000096717 SIRT1 ENSG00000196914 ARHGEF12 H. sapiens SSL Slorth 0.790852 View
ENSG00000096717 SIRT1 ENSG00000121966 CXCR4 H. sapiens SSL Slorth 0.790584 View
ENSG00000096717 SIRT1 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.790518 View
ENSG00000096717 SIRT1 ENSG00000185386 MAPK11 H. sapiens SSL Slorth 0.790503 View
ENSG00000096717 SIRT1 ENSG00000110171 TRIM3 H. sapiens SSL Slorth 0.790474 View
ENSG00000096717 SIRT1 ENSG00000117614 SYF2 H. sapiens SSL Slorth 0.789981 View
ENSG00000096717 SIRT1 ENSG00000164941 INTS8 H. sapiens SSL Slorth 0.789822 View
ENSG00000096717 SIRT1 ENSG00000100721 TCL1A H. sapiens SSL Slorth 0.789664 View
ENSG00000096717 SIRT1 ENSG00000141380 SS18 H. sapiens SSL Slorth 0.789613 View
ENSG00000009335 UBE3C ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.789393 View
ENSG00000096717 SIRT1 ENSG00000127948 POR H. sapiens SSL Slorth 0.78938 View
ENSG00000081189 MEF2C ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.789298 View
ENSG00000096717 SIRT1 ENSG00000188191 PRKAR1B H. sapiens SSL Slorth 0.789229 View
ENSG00000096717 SIRT1 ENSG00000155097 ATP6V1C1 H. sapiens SSL Slorth 0.789101 View
ENSG00000096717 SIRT1 ENSG00000105971 CAV2 H. sapiens SSL Slorth 0.788687 View
ENSG00000096717 SIRT1 ENSG00000124217 MOCS3 H. sapiens SSL Slorth 0.788593 View
ENSG00000096717 SIRT1 ENSG00000223443 USP17L2 H. sapiens SSL Slorth 0.78795 View
ENSG00000096717 SIRT1 ENSG00000163902 RPN1 H. sapiens SSL Slorth 0.787773 View
ENSG00000096717 SIRT1 ENSG00000111199 TRPV4 H. sapiens SSL Slorth 0.787648 View
ENSG00000096717 SIRT1 ENSG00000184445 KNTC1 H. sapiens SSL Slorth 0.787411 View
ENSG00000096717 SIRT1 ENSG00000168959 GRM5 H. sapiens SSL Slorth 0.787271 View
ENSG00000096717 SIRT1 ENSG00000175220 ARHGAP1 H. sapiens SSL Slorth 0.787181 View
ENSG00000096717 SIRT1 ENSG00000133318 RTN3 H. sapiens SSL Slorth 0.786904 View
ENSG00000096717 SIRT1 ENSG00000132388 UBE2G1 H. sapiens SSL Slorth 0.786833 View
ENSG00000096717 SIRT1 ENSG00000176601 MAP3K19 H. sapiens SSL Slorth 0.786819 View
ENSG00000096717 SIRT1 ENSG00000160551 TAOK1 H. sapiens SSL Slorth 0.786623 View